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Translational Neuropsychiatry Unit

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Bouzinova, E., Wiborg, O., Aalkjær, C. & Matchkov, V. (2015). Role of Peripheral Vascular Resistance for the Association Between Major Depression and Cardiovascular Disease. Journal of Cardiovascular Pharmacology, 65(4), 1-9. https://doi.org/10.1097/FJC.0000000000000187

Hjorth, P., Kilian, R., Sørensen, H. Ø., Eriksen, S. E., Davidsen, A. S., Jensen, S. O. W. & Munk-Jørgensen, P. (2015). Reducing psychotropic pharmacotherapy in patients with severe mental illness: a cluster-randomized controlled intervention study. Therapeutic advances in psychopharmacology, 5(2), 67-75. https://doi.org/10.1177/2045125314565361

Landau, A. M., Phan, J-A., Iversen, P., Lillethorup, T. P., Simonsen, M., Wegener, G. ... Doudet, D. J. (2015). Decreased in vivo α2 adrenoceptor binding in the Flinders Sensitive Line rat model of depression. Neuropharmacology, 91, 97-102. https://doi.org/10.1016/j.neuropharm.2014.12.025

Thomsen, M., Lillethorup, T. P., Wegener, G., Tasker, A. & Landau, A. M. (2015). Neonatal domoic acid increases receptor density of α2 adrenoceptors and GABAA α5 receptors in limbic brain regions of adult rats. Poster session presented at 56th Annual Congress of the Scandinavian College of Neuro-Psychopharmacology, Copenhagen, Denmark.

Bjerregaard, H., Severinsen, K., Said, S., Wiborg, O. & Sinning, S. (2015). A dualistic conformational response to substrate binding in the human serotonin transporter reveals a high affinity state for serotonin. Journal of Biological Chemistry, 290(12), 7747-55. https://doi.org/10.1074/jbc.M114.573477

Slattery, D. A., Naik, R. R., Grund, T., Yen, Y-C., Sartori, S. B., Füchsl, A. ... Neumann, I. D. (2015). Selective breeding for high anxiety introduces a synonymous SNP that increases neuropeptide s receptor activity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(11), 4599-613. https://doi.org/10.1523/JNEUROSCI.4764-13.2015

Pyndt Jørgensen, B., Winther, G., Kihl, P., Nielsen, D. S., Wegener, G., Hansen, A. K. & Sørensen, D. B. (2015). Dietary magnesium deficiency affects gut microbiota and anxiety-like behaviour in C57BL/6N mice. Acta Neuropsychiatrica (Print), 1-5. https://doi.org/10.1017/neu.2015.10

Strenn, N., Suchankova, P., Nilsson, S., Fischer, C., Wegener, G., Mathé, A. A. & Ekman, A. (2015). Expression of inflammatory markers in a genetic rodent model of depression. Behavioural Brain Research, 281, 348–357. https://doi.org/10.1016/j.bbr.2014.09.025

Nieto-Gonzalez, J. L., Holm, M. M., Vardya, I., Christensen, T., Wiborg, O. & Jensen, K. (2015). Presynaptic Plasticity as a Hallmark of Rat Stress Susceptibility and Antidepressant Response. P L o S One, 10(3).

Czéh, B., Varga, Z. K. K., Henningsen, K., Kovács, G. L., Miseta, A. & Wiborg, O. (2015). Chronic stress reduces the number of GABAergic interneurons in the adult rat hippocampus, dorsal-ventral and region-specific differences. The Hippocampus, 25(3), 393-405. https://doi.org/10.1002/hipo.22382

Lillethorup, T. P., Iversen, P., Fontain, J., Wegener, G., Doudet, D. J. & Landau, A. M. (2015). Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 404-412. https://doi.org/10.1016/j.euroneuro.2014.12.003

Vandborg, S. K., Hartmann, T. B., Bennedsen, B. E., Pedersen, A. D. & Thomsen, P. H. (2015). Are there reliable changes in memory and executive functions after cognitive behavioural therapy in patients with obsessive-compulsive disorder? Cognitive Neuropsychiatry, 20(2), 128-43. https://doi.org/10.1080/13546805.2014.981649

Winther, G., Pyndt Jørgensen, B. M., Elfving, B., Nielsen, D. S., Kihl, P., Lund, S. ... Wegener, G. (2015). Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour. Acta Neuropsychiatrica (Print), 1-9. https://doi.org/10.1017/neu.2015.7

Elfving, B., Jakobsen, J. L., Madsen, J. C. B., Wegener, G. & Müller, H. K. (2015). Chronic restraint stress increases the protein expression of VEGF and its receptor VEGFR-2 in the prefrontal cortex. Synapse. https://doi.org/10.1002/syn.21808

Pereira, V. S., Romano, A., Wegener, G. & Joca, S. (2015). Antidepressant-like effects induced by NMDA receptor blockade and NO synthesis inhibition in the ventral medial prefrontal cortex of rats exposed to the forced swim test. Psychopharmacology. https://doi.org/10.1007/s00213-014-3853-2

Rajkumar, A. P., Christensen, J. H., Mattheisen, M., Jacobsen, I., Bache, I., Pallesen, J. ... Børglum, A. D. (2015). Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder. Bipolar Disorders (English Edition, Online), 17(2), 205-211. https://doi.org/10.1111/bdi.12239

Kravtsova, V., Matchkov, V., Bouzinova, E., Vasiliev, AN., Razgovorova, IA., Heiny, JA. & Krivoi, II. (2015). Isoform-specific Na,K-ATPase alterations precede disuse-induced atrophy of rat soleus muscle. BioMed Research International. https://doi.org/10.1155/2015/720172

Kristiansen, C. B., Kjaer, J. N., Medici, C. R., Kai, L. M. & Okkels, N. (2015). Future perspectives on psychiatry. Acta Psychiatrica Scandinavica, 131(1), 8-9. https://doi.org/10.1111/acps.12360

Bay-Richter, C., Linderholm, K. R., Lim, CK., Samuelsson, M., Träskman-Bendz, L., Guillemin, G. J. ... Brundin, L. (2015). A role for inflammatory metabolites as modulators of the glutamate N-methyl-d-aspartate receptor in depression and suicidality. Brain, Behavior, and Immunity, 43, 110-117. https://doi.org/10.1016/j.bbi.2014.07.012

Buttenschøn, H. N., Demontis, D., Ollendorff, M. K., Elfving, B., Jensen, S. M., Gustafsen, C. ... Pedersen, S. G. (2015). Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF. Translational Psychiatry, 5(e677). https://doi.org/10.1038/tp.2015.167

Buttenschøn, H. N., Demontis, D., Kaas, M., Elfving, B., mølgaard, S., Gustafsen, C. ... Pedersen, S. G. (2015). Increased sortilin in depression.

Chen, F., Rosenberg, R., Nyengaard, J. R. & Dorph-Petersen, K-A. (2015). Hippocampus in depression, schizophrenia, and suicide: a postmortem stereological study of hippocampal volume and cell number. Abstract from 31st Nordic Congress of Psychiatry (NCP 2015), Copenhagen, Denmark.

Chen, F., Rosenberg, R., Nyengaard, J. R. & Dorph-Petersen, K-A. (2015). Volume and cell number of the human hippocampus: a postmortem stereological study of hippocampus in depression, schizophrenia, and suicide. In 14th International Congress of Stereology and Image Analysis. Proceedings: Exploring New Dimensions in Imaging

Dorph-Petersen, K-A. & Lewis, D. A. (2015). Changes in brain structure in monkeys and rats following exposure to antipsychotic medication. Abstract from 31st Nordic Congress of Psychiatry (NCP 2015), Copenhagen, Denmark.

Dorph-Petersen, K-A. & Lewis, D. A. (2015). Chronic exposure to antipsychotic medication changes the brain structure in monkeys and rats. Schizophrenia Bulletin, 41 (Suppl 1), S3. https://doi.org/10.1093/schbul/sbv010

Dorph-Petersen, K-A., Rosenberg, R., Nyengaard, J. R. & Chen, F. (2015). Hippocampus in schizophrenia, depression, and suicide: a postmortem stereological study of hippocampal volume and cell number. Schizophrenia Bulletin, 41 (Suppl 1), S286. https://doi.org/10.1093/schbul/sbv010

Fischer, C. (2015). Challenging the immune system in rodents and its association to depression.

Gregersen, N. (2015). Identification and analyses of genetic risk factors for panic disorder.

Howe, AS., Buttenschøn, H. N., Bani-Fatemi, A., Maron, E., Otowa, T., Erhardt, A. ... De Luca, V. (2015). Candidate genes in panic disorder: metaanalyses of 23 common variants in major anxiogenic pathways. Molecular Psychiatry.

Joca, S., Moreira, F. A. & Wegener, G. (2015). Atypical neurotransmitters and the neurobiology of depression. CNS & neurological disorders drug targets, 14 (8), 1001-11. https://doi.org/10.2174/1871527314666150909114804

Kai, L. M. (2015). Psykiatri på psykiatriens betingelser. Ugeskrift for Læger, 2015(1).

Kai, L. M., Elfving, B. & Wegener, G. (2015). The characteristic secret whistles of a depressive-like rat. Poster session presented at Psykiatriens 10. forskningsdag, Risskov, Denmark.

Khan, A. R., Chuhutin, A., Hansen, B., Wiborg, O., Kroenke, C. & Jespersen, S. N. (2015). Biophysical Modeling of High Field Diffusion MRI Demonstrates Micro-Structural Aberration in Chronic Mild Stress (CMS) Rat Brain. Abstract from ISMRM 2015 23rd Annual Meeting, Toronto, Canada.

Kousholt, B. & Wegener, G. (2015). Større metodisk tilgang efterlyses i dyrestudier. Dansk Veterinaertidsskrift, 98(12), 27-30.

Krass, M., Volke, A., Rünkorg, K., Wegener, G., Lund, S., Abildgaard, A. ... Volke, V. (2015). GLP-1 receptor agonists have a sustained stimulatory effect on corticosterone release after chronic treatment. Acta Neuropsychiatrica (Print), 27(1), 25-32. https://doi.org/10.1017/neu.2014.36

Medici, C. R., Vestergaard, C. H., Hjorth, P., Hansen, M. V., Shanmuganathan, J. W., Viuff, A. G. & Munk-Jørgensen, P. (2015). Quality of life and clinical characteristics in a nonselected sample of patients with schizophrenia. The International journal of social psychiatry. https://doi.org/10.1177/0020764015585330

Musazzi, L., Tornese, P., Treccani, G. & Popoli, M. (2015). SSRIs and glutamate release and transmission, in: "Fluoxetine/SSRI: Pharmacology, Mechanisms of Action and Potential Side Effects. In Fluoxetine/SSRI: Pharmacology, Mechanisms of Action and Potential Side Effects Nova Science Publishers.

Musazzi, L., Treccani, G., Milanese, M., Perego, C., Nava, N., Tornese, P. ... Popoli, M. (2015). The stress impact on synaptic function and brain architecture; a key to mood and anxiety disorders. Poster session presented at 28th Congress of the European-College-of-Neuropsychopharmacology (ECNP), Amsterdam, Netherlands.

Popoli, M., Musazzi, L., Tornese, P., Sala, N., Treccani, G., Bazzini, C. ... Nava, N. (2015). Time-dependent changes induced by acute stress in function and architecture of excitatory synapses in prefrontal and frontal cortex. Poster session presented at Neuroscience 2015, Chicago, IL, United States.

Smith, D. F. (2015). Gluten-free Diet And Psychic Depression i Celiac Disease. In Gluten-Free Diets: Food Sources, Role in Celiac Disease and Health Benefits (pp. 51-62). New York: Nova Science Publishers.

Treccani, G., Nava, N., Musazzi, L., Milanese, M., Perego, C., Bonifacino, T. ... Wegener, G. (2015). Time-dependent effects of acute stress on glutamate synapse. Poster session presented at CINP CINP Thematic Meeting on Stress, inflammation and depression: focus on novel antidepressant targets .

Treccani, G., Nava, N., Musazzi, L., Milanese, M., Perego, C., Bonifacino, T. ... Wegener, G. (2015). Time-dependent effects of acute stress on glutamate synapse. Poster session presented at The Brain Prize Meeting 2015, Middelfart, Denmark.

Treccani, G., du Jardin, K. G., Wegener, G. & Müller, H. K. (2015). Time-dependent functional changes induced by ketamine in the glutamate system: focus on glutamate release, glutamate receptors and dendritic morphology. Poster session presented at 56th Annual Conference if the SCNP, Copenhagen, Denmark.

Wei, Y., Melas, P. A., Wegener, G., Mathé, A. A. & Lavebratt, C. (2015). Antidepressant-Like Effect of Sodium Butyrate is Associated with an Increase in TET1 and in 5-Hydroxymethylation Levels in the Bdnf Gene. International Journal of Neuropsychopharmacology, 18(2). https://doi.org/10.1093/ijnp/pyu032

Wei, Y., Backlund, L., Wegener, G., Mathe, A. A. & Lavebratt, C. (2015). Telomerase dysregulation in the hippocampus of a rat model of depression. Normalization by lithium. International Journal of Neuropsychopharmacology. https://doi.org/10.1093/ijnp/pyv002

du Jardin, K. G., Liebenberg, N., Müller, H. K., Elfving, B., Sánchez, C. & Wegener, G. (2015). Differentiated antidepressant-like profiles of ketamine, fluoxetine and vortioxetine in Flinders Sensitive Line rats depleted of endogenous 5-HT. Acta Neuropsychiatrica, 27(S1). https://doi.org/10.1017/neu.2015.26

du Jardin, K. G., Liebenberg, N., Müller, H. K., Wegener, G., Sánchez, C. & Elfving, B. (2015). P90. Differentiated antidepressantlike profiles of ketamine, fluoxetine and vortioxetine in Flinders Sensitive Line rats depleted of endogenous 5-HT—An approach to gain new mechanistic insights?. Poster session presented at 48th Annual Winter Conference on Brain Research, Big Sky, MO, United States.

Smith, D. F. & Jakobsen, S. (2014). Minireview of Stereoselective Brain Imaging. Archives of Current Research International, 1(1), 1-16. [ACRI.2014.001]. https://doi.org/10.9734/ACRI/2014/14787

Nava, N., Treccani, G., Liebenberg, N., Chen, F., Popoli, M., Wegener, G. & Nyengaard, J. R. (2014). Chronic desipramine prevents acute stress-induced reorganization of medial prefrontal cortex architecture by blocking glutamate vesicle accumulation and excitatory synapse increase. International Journal of Neuropsychopharmacology. https://doi.org/10.1093/ijnp/pyu085

Liebenberg, N., Joca, S. & Wegener, G. (2014). Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression. Acta Neuropsychiatrica, 1-7. https://doi.org/10.1017/neu.2014.39

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Revised 21.11.2019