Overby, M., Serrano-Rodriguez, A., Dadras, S.
, Christiansen, A. K., Ozcelik, G., Lichtenthaler, S. F., Weick, J. P.
& Müller, H. K. (2023).
Neuron-specific gene NSG1 binds to and positively regulates sortilin ectodomain shedding via a metalloproteinase-dependent mechanism.
The Journal of Biological Chemistry,
299(12), 105446. Article 105446.
https://doi.org/10.1016/j.jbc.2023.105446
Biojone, C., C Casarotto, P., Cannarozzo, C., Fred, S. M., Herrera-Rodríguez, R., Lesnikova, A., Voipio, M. & Castrén, E. (2023).
nNOS-induced tyrosine nitration of TRKB impairs BDNF signaling and restrains neuronal plasticity.
Progress in Neurobiology,
222, Article 102413.
https://doi.org/10.1016/j.pneurobio.2023.102413
Højgaard, K., Szöllősi, B., Henningsen, K., Minami, N., Nakanishi, N.
, Kaadt, E., Tamura, M., Morris, R. G. M.
, Takeuchi, T. & Elfving, B. (2023).
Novelty-induced memory consolidation is accompanied by increased Agap3 transcription: a cross-species study.
Molecular Brain,
16(1), Article 69.
https://doi.org/10.1186/s13041-023-01056-4
Arjmand, S., Bender, D., Jakobsen, S., Wegener, G. & Landau, A. M. (2023).
Peering into the Brain's Estrogen Receptors: PET Tracers for Visualization of Nuclear and Extranuclear Estrogen Receptors in Brain Disorders.
Biomolecules,
13(9), Article 1405.
https://doi.org/10.3390/biom13091405
Wang, X., Walker, A., Revez, J. A., Ni, G., Adams, M. J., McIntosh, A. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2023).
Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability.
American Journal of Human Genetics,
110(7), 1207-1215.
https://doi.org/10.1016/j.ajhg.2023.06.006
Kirkeby, A., Nelander, J., Hoban, D. B., Rogelius, N., Bjartmarz, H., Novo Nordisk Cell Therapy R&D, Storm, P., Fiorenzano, A., Adler, A. F., Vale, S., Mudannayake, J., Zhang, Y., Cardoso, T., Mattsson, B.
, Landau, A. M., Glud, A. N., Sørensen, J. C., Lillethorup, T. P., Lowdell, M. ... Parmar, M. (2023).
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD.
Cell Stem Cell,
30(10), 1299-1314.e9.
https://doi.org/10.1016/j.stem.2023.08.014
Gravina, G.
, Ardalan, M., Chumak, T., Nilsson, A. K., Ek, J. C., Danielsson, H., Svedin, P., Pekny, M., Pekna, M., Sävman, K., Hellström, A. & Mallard, C. (2023).
Proteomics identifies lipocalin-2 in neonatal inflammation associated with cerebrovascular alteration in mice and preterm infants.
iScience,
26(7), Article 107217.
https://doi.org/10.1016/j.isci.2023.107217
Moliner, R., Girych, M., Brunello, C. A., Kovaleva, V.
, Biojone, C., Enkavi, G., Antenucci, L., Kot, E. F., Goncharuk, S. A., Kaurinkoski, K., Kuutti, M., Fred, S. M., Elsilä, L. V., Sakson, S., Cannarozzo, C., Diniz, C. R. A. F., Seiffert, N., Rubiolo, A., Haapaniemi, H. ... Castrén, E. (2023).
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB.
Nature Neuroscience,
26(6), 1032-1041.
https://doi.org/10.1038/s41593-023-01316-5
Dósa, Z., Nieto-Gonzalez, J. L.
, Elfving, B., Hougaard, K. S.
, Holm, M. M., Wegener, G. & Jensen, K. (2023).
Reduction in hippocampal GABAergic transmission in a low birth weight rat model of depression.
Acta Neuropsychiatrica,
35(6), 1-34.
https://doi.org/10.1017/neu.2023.18
Oka, N., Sakoh, M., Hirayama, M., Niiyama, M.
& Gjedde, A. (2023).
Relationship between manual dexterity and left–right asymmetry of anatomical and functional properties of corticofugal tracts revealed by T2-weighted brain images.
Scientific Reports,
13(1), Article 2738.
https://doi.org/10.1038/s41598-023-29557-1
Kousholt, B. S., Præstegaard, K. F., Stone, J. C.
, Thomsen, A. F., Johansen, T. T., Ritskes-Hoitinga, M. & Wegener, G. (2023).
Reporting of 3Rs Approaches in Preclinical Animal Experimental Studies—A Nationwide Study.
Animals,
13(19), Article 3005.
https://doi.org/10.3390/ani13193005
Zhai, R., Tong, G., Li, Z., Song, W., Hu, Y., Xu, S., Wei, Q., Zhang, X., Li, Y., Liao, B., Yuan, C., Fan, Y., Song, G., Ouyang, Y., Zhang, W., Tang, Y., Jin, M., Zhang, Y., Li, H. ... Wang, Z. (2023).
Rhesus monkeys exhibiting spontaneous ritualistic behaviors resembling obsessive-compulsive disorder.
National Science Review,
10(11), Article nwad312.
https://doi.org/10.1093/nsr/nwad312
Real, C. C., Binda, K. H., Thomsen, M. B., Lillethorup, T. P., Brooks, D. J. & Landau, A. M. (2023).
Selecting the Best Animal Model of Parkinson's Disease for Your Research Purpose: Insight from in vivo PET Imaging Studies.
Current Neuropharmacology,
21(5), 1241 - 1272.
https://doi.org/10.2174/1570159X21666230216101659
Arjmand, S., Vadstrup Pedersen, M., Silva, N. R., Landau, A. M., Joca, S. & Wegener, G. (2023).
Sex and Estrous Cycle Are Not Mediators of S-Ketamine's Rapid-Antidepressant Behavioral Effects in a Genetic Rat Model of Depression.
The international journal of neuropsychopharmacology,
26(5), 350–358.
https://doi.org/10.1093/ijnp/pyad016
Krogsbaek, M., Larsen, N. Y., Landau, A. M., Sanchez, C. & Nyengaard, J. R. (2023).
Spatial quantification of single cell mRNA and ligand binding of the kappa opioid receptor in the rat hypothalamus.
Journal of Chemical Neuroanatomy,
127, Article 102205.
https://doi.org/10.1016/j.jchemneu.2022.102205
Burmester, D. R., Madsen, M. K., Szabo, A., Aripaka, S. S., Stenbæk, D. S., Frokjaer, V. G.
, Elfving, B., Mikkelsen, J. D., Knudsen, G. M. & Fisher, P. M. (2023).
Subacute effects of a single dose of psilocybin on biomarkers of inflammation in healthy humans: An open-label preliminary investigation.
Comprehensive Psychoneuroendocrinology,
13, Article 100163.
https://doi.org/10.1016/j.cpnec.2022.100163
Haupt, T. H.
, Elfving, B., Eugen-Olsen, J.
, Mors, O. & Köhler-Forsberg, O. (2023).
SuPAR in major depression: Association with 26 weeks antidepressant response and 10-year depression outcomes.
Brain, Behavior, and Immunity - Health,
33, Article 100685.
https://doi.org/10.1016/j.bbih.2023.100685
Bak, S. T., Haupt-Jorgensen, M., Dudele, A.
, Wegener, G., Wang, T., Nielsen, A. L. & Lund, S. (2023).
The anti-inflammatory agent 5-ASA reduces the level of specific tsRNAs in sperm cells of high-fat fed C57BL/6J mouse sires and improves glucose tolerance in female offspring.
Journal of Diabetes and its Complications,
37(9), Article 108563.
https://doi.org/10.1016/j.jdiacomp.2023.108563
Karsberg, S. H., Thylstrup, B., Thomsen, K. R., Grassi-Oliveira, R., Pedersen, M. M. & Hesse, M. (Accepted/In press).
The Impact of Severe Trauma Exposure in Late Childhood on Longitudinal Treatment Outcomes in Adolescents and Young Adults in Treatment for Drug Use Disorders: A Record-Linkage Study.
International Journal of Mental Health and Addiction.
https://doi.org/10.1007/s11469-023-01182-z
Krivosova, M., Adamcakova, J.
, Kaadt, E., Mumm, B. H., Dvorska, D., Brany, D., Dankova, Z., Dohal, M., Samec, M., Ferencova, N., Tonhajzerova, I., Ondrejka, I., Hrtanek, I., Hutka, P., Oppa, M., Mokry, J.
& Elfving, B. (2023).
The VEGF protein levels, miR-101-3p, and miR-122-5p are dysregulated in plasma from adolescents with major depression.
Journal of Affective Disorders,
334, 60-68.
https://doi.org/10.1016/j.jad.2023.04.094
Chalmers, S. B., Madgwick, S., Lloyd-Lewis, B., McClurg, U. L., Elias, S.
, Andersen, P., Madsen, R., Ananthanarayanan, V.
& Davis, F. M. (2023).
Towards inclusive and sustainable scientific meetings.
Nature Cell Biology,
25(11), 1557-1560.
https://doi.org/10.1038/s41556-023-01222-9
Gravina, G.
, Ardalan, M., Chumak, T., Rydbeck, H., Wang, X., Ek, C. J. & Mallard, C. (2023).
Transcriptome network analysis links perinatal Staphylococcus epidermidis infection to microglia reprogramming in the immature hippocampus.
Glia,
71(9), 2234-2249.
https://doi.org/10.1002/glia.24389
Henrique Binda, K., Landau, A. M., Chacur, M.
, Brooks, D. J. & Cristiano Real, C. (2023).
Treadmill exercise modulates nigral and hippocampal cannabinoid receptor type 1 in the 6-OHDA model of Parkinson's disease.
Brain Research,
1814, Article 148436.
https://doi.org/10.1016/j.brainres.2023.148436
Creutzberg, K. C., Begni, V., Orso, R., Lumertz, F. S., Wearick-Silva, L. E., Tractenberg, S. G., Marizzoni, M., Cattaneo, A.
, Grassi-Oliveira, R. & Riva, M. A. (2023).
Vulnerability and resilience to prenatal stress exposure: behavioral and molecular characterization in adolescent rats.
Translational Psychiatry,
13(1), Article 358.
https://doi.org/10.1038/s41398-023-02653-6
Kousholt, B. S., Præstegaard, K. F., Stone, J. C.
, Thomsen, A. F., Johansen, T. T., Ritskes-Hoitinga, M. & Wegener, G. (2022).
3R reporting in preclinical animal studies in 2009 and 2018 - a nationwide study.
Laboratory Animals,
56(1, suppl.), 29-30.
https://doi.org/10.1177/00236772221103950
Andersen, O. M., Bøgh, N., Landau, A. M., Pløen, G. G., Jensen, A. M. G., Monti, G., Ulhøi, B. P.
, Nyengaard, J. R., Jacobsen, K. R.
, Jørgensen, M. M., Holm, I. E., Kristensen, M. L.
, Alstrup, A. K. O., Hansen, E. S. S., Teunissen, C. E., Breidenbach, L., Droescher, M., Liu, Y., Pedersen, H. S.
... Sørensen, C. B. (2022).
A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.
Cell Reports Medicine,
3(9), Article 100740.
https://doi.org/10.1016/j.xcrm.2022.100740
Virtuoso, A., Tveden‐Nyborg, P., Schou‐pedersen, A. M. V., Lykkesfeldt, J.
, Müller, H. K., Elfving, B. & Sørensen, D. B. (2022).
A long‐term energy‐rich diet increases prefrontal BDNF in Sprague‐Dawley rats.
Nutrients,
14(1), Article 126.
https://doi.org/10.3390/nu14010126
Gasse, C., Otte, C., Gold, S. M.
, Elfving, B., Mors, O. & Köhler-Forsberg, O. (2022).
Association between cholesterol and response to escitalopram and nortriptyline in patients with major depression: Study combining clinical and register-based information.
Biomarkers in Neuropsychiatry,
7, Article 100057.
https://doi.org/10.1016/j.bionps.2022.100057
Chrusciel, J. H., Orso, R., de Mattos, B. P., Fries, G. R., Kristensen, C. H.
, Grassi-Oliveira, R. & Viola, T. W. (2022).
A systematic review and meta-analysis of epigenetic clocks in schizophrenia.
Schizophrenia Research,
246, 172-174.
https://doi.org/10.1016/j.schres.2022.06.029
Marquez-Legorreta, E., Constantin, L., Piber, M., Favre-Bulle, I. A., Taylor, M. A., Blevins, A. S., Giacomotto, J., Bassett, D. S.
, Vanwalleghem, G. C. & Scott, E. K. (2022).
Brain-wide visual habituation networks in wild type and fmr1 zebrafish.
Nature Communications,
13(1), Article 895.
https://doi.org/10.1038/s41467-022-28299-4
Andersen, F. D.
, Joca, S., Hvingelby, V., Arjmand, S., Pinilla, E., Comerma Steffensen, S. G., Simonsen, U. & Andersen, C. U. (2022).
Combined effects of quetiapine and opioids: A study of autopsy cases, drug users and sedation in rats .
Addiction Biology (Online),
27(5), Article e13214.
https://doi.org/10.1111/adb.13214
Kousholt, B. S., Præstegaard, K. F., Stone, J. C.
, Thomsen, A. F., Johansen, T. T., Ritskes-Hoitinga, M. & Wegener, G. (2022).
Comparing reporting quality of preclinical animal studies in 2009 versus 2018 – a nationwide study.
Laboratory Animals,
56(1, suppl.), 172.
https://doi.org/10.1177/00236772221103950
Kofod, J.
, Elfving, B., Nielsen, E. H.
, Mors, O. & Köhler-Forsberg, O. (2022).
Depression and inflammation: Correlation between changes in inflammatory markers with antidepressant response and long-term prognosis.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology,
54, 116-125.
https://doi.org/10.1016/j.euroneuro.2021.09.006
Badr, S., MacCallum, B., Madadian, E., Kerr, G., Naseri, E., MacDonald, D., Bodaghkhani, A.
, Tasker, R. A. & Ahmadi, A. (2022).
Development of a mist-based printhead for droplet-based bioprinting of ionically crosslinking hydrogel bioinks.
Bioprinting,
27, Article e00207.
https://doi.org/10.1016/j.bprint.2022.e00207
Al-Absi, A.-R., Thambiappa, S. K., Khan, A. R.
, Glerup, S., Sanchez, C., Landau, A. M. & Nyengaard, J. R. (2022).
Df(h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus.
Molecular and Cellular Neuroscience,
122, Article 103769.
https://doi.org/10.1016/j.mcn.2022.103769
Larsen, E. R., Juel, A., Jensen, E., Hollyer, T. R.
& Wegener, G. (2022).
Dietary Supplementation with Casein Glycomacropeptide, Leucine and Tryptophan Reduces Plasma Amino Acid Levels in Men.
Acta Neuropsychiatrica,
34(2), 69-76.
https://doi.org/10.1017/neu.2021.34
Sigvard, A. K., Nielsen, M. Ø.
, Gjedde, A., Bojesen, K. B., Fuglø, D., Tangmose, K., Kumakura, Y., Heltø, K., Ebdrup, B. H., Jensen, L. T., Rostrup, E. & Glenthøj, B. Y. (2022).
Dopaminergic Activity in Antipsychotic-Naïve Patients Assessed With Positron Emission Tomography Before and After Partial Dopamine D2 Receptor Agonist Treatment: Association With Psychotic Symptoms and Treatment Response.
Biological Psychiatry,
91(2), 236-245.
https://doi.org/10.1016/j.biopsych.2021.08.023