Chen, F., Danladi, J., Ardalan, M., Elfving, B., Müller, H. K., Wegener, G., Sanchez, C. & Nyengaard, J. R. (2018).
A critical role of mitochondria in BDNF-associated synaptic plasticity after one-week vortioxetine treatment.
International Journal of Neuropsychopharmacology,
21(6), 603-615.
https://doi.org/10.1093/ijnp/pyy022
Bertelsen, F., Landau, A. M., Vase, K. H., Jacobsen, J., Scheel-Krüger, J. & Møller, A. (2018).
Acute in vivo effect of valproic acid on the GABAergic system in rat brain: A [C-11]Ro15-4513 microPET study.
Brain Research,
1680, 110-114.
https://doi.org/10.1016/j.brainres.2017.12.018
Zeppelin, T., Ladefoged, L. K., Sinning, S., Periole, X. & Schiøtt, B. (2018).
A direct interaction of cholesterol with the dopamine transporter prevents its out-to-inward transition.
PLoS Computational Biology,
14(1), Article e1005907.
https://doi.org/10.1371/journal.pcbi.1005907
Diniz, C. R. A. F., Casarotto, P., Fred, S. M.
, Biojone, C., Castren, E.
& Joca, S. (2018).
Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN.
Neuropharmacology.
de Jong, S., Diniz, M. J. A., Saloma, A., Gadelha, A., Santoro, M. L., Ota, V. K., Noto, C., Curtis, C., Newhouse, S. J., Patel, H., Hall, L. S., O Reilly, P. F., Belangero, S. I., Bressan, R. A., Breen, G. & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (Per Qvist and Preben Bo Mortensen, members of-) (2018).
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.
Communications Biology,
1(1), Article 163.
https://doi.org/10.1038/s42003-018-0155-yLiebenberg, N., Jensen, E., Larsen, E. R., Kousholt, B. S., Pereira, V. S., Fischer, C. W. & Wegener, G. (2018).
A Preclinical Study of Casein Glycomacropeptide as a Dietary Intervention for Acute Mania.
International Journal of Neuropsychopharmacology,
21(5), 473-484.
https://doi.org/10.1093/ijnp/pyy012
Qvist, P., Eskildsen, S. F., Hansen, B., Baragji, M., Ringgaard, S., Roovers, J.
, Paternoster, V., Molgaard, S., Corydon, T. J., Stødkilde-Jørgensen, H., Glerup, S., Mors, O., Wegener, G., Nyengaard, J. R., Børglum, A. D. & Christensen, J. H. (2018).
Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/- mice.
Scientific Reports,
8(1), 16486. Article 16486.
https://doi.org/10.1038/s41598-018-34729-5
Laursen, L., Kristensen, K. B., Periole, X., Overby, M., Müller, H. K., Schiøtt, B. & Sinning, S. (2018).
Cholesterol binding to a conserved site modulates conformation, pharmacology and transport kinetics of the human serotonin transporter.
Journal of Biological Chemistry,
293(10), 3510-3523.
https://doi.org/10.1074/jbc.M117.809046
van der Kooij, M. A., Jene, T.
, Treccani, G., Miederer, I., Hasch, A., Voelxen, N., Walenta, S. & Müller, M. B. (2018).
Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory.
Proceedings of the National Academy of Sciences (PNAS),
115(43), E10187-E10196.
https://doi.org/10.1073/pnas.1804412115Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. A. F., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A., Baune, B. T. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2018).
Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.
Biological Psychiatry,
84(2), 138-147.
https://doi.org/10.1016/j.biopsych.2017.09.009Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W.
, Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S.-H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M. ... Lewis, C. M. (2018).
Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology,
28(8), 945-954.
https://doi.org/10.1016/j.euroneuro.2018.05.009Diniz, C. R. A. F., Becari, C., Lesnikova, A.
, Biojone, C., Salgado, M. C. O., Salgado, H. C., Resstel, L. B. M., Guimaraes, F. S., Castren, E., Casarotto, P.
& Joca, S. (2018).
Elastase-2 Knockout Mice Display Anxiogenic- and Antidepressant-Like Phenotype: Putative Role for BDNF Metabolism in Prefrontal Cortex.
Molecular Neurobiology.
Landau, A. M., Alstrup, A. K. O., Audrain, H., Jakobsen, S., Simonsen, M., Møller, A., Videbech, P. B.
, Wegener, G., Gjedde, A. & Doudet, D. J. (2018).
Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy.
Journal of Cerebral Blood Flow and Metabolism,
38(5), 881-887.
https://doi.org/10.1177/0271678X17705260
Severino, M., Sivasaravanaparan, M., Olesen, L., von Linstow, C. U., Metaxas, A.
, Bouzinova, E. V., Khan, A. M., Lambertsen, K. L., Babcock, A. A., Gramsbergen, J. B.
, Wiborg, O. & Finsen, B. (2018).
Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine.
Alzheimer's & Dementia: Translational Research & Clinical Interventions,
4, 215-223.
https://doi.org/10.1016/j.trci.2018.04.005Wang, Q., Liao, J., Hair, K.
, Bannach-Brown, A., Bahor, Z., Currie, G. L., McCann, S. K., Howells, D. W., Sena, E. S. & Macleod, M. R. (2018).
Estimating the statistical performance of different approaches to meta-analysis of data from animal studies in identifying the impact of aspects of study design.
http://biorxiv.org/content/early/2018/01/30/256776.abstractBak, S. T., Staunstrup, N. H., Starnawska, A., Daugaard, T. F., Nyengaard, J. R., Nyegaard, M., Børglum, A., Mors, O., Dorph-Petersen, K.-A. & Nielsen, A. L. (2018).
Evaluating the Feasibility of DNA Methylation Analyses Using Long-Term Archived Brain Formalin-Fixed Paraffin-Embedded Samples.
Molecular Neurobiology,
55(1), 668-681.
https://doi.org/10.1007/s12035-016-0345-x
Buttenschøn, H. N., Elfving, B., Nielsen, M., Skeldal, S.
, Kaas, M., Mors, O. & Glerup, S. (2018).
Exploring the sortilin related receptor, SorLA, in depression.
Journal of Affective Disorders,
232, 260-267.
https://doi.org/10.1016/j.jad.2018.02.050
Masana, M., Westerholz, S., Kretzschmar, A.
, Treccani, G., Liebl, C., Santarelli, S., Dournes, C., Popoli, M., Schmidt, M. V., Rein, T. & Müller, M. B. (2018).
Expression and glucocorticoid-dependent regulation of the stress-inducible protein DRR1 in the mouse adult brain.
Brain Structure & Function,
223(9), 4039–4052.
https://doi.org/10.1007/s00429-018-1737-7Knudsen, J. K., Bundgaard-Nielsen, C.
, Hagstrøm, S., Sørensen, S. & Leutscher, P. (2018).
geneksDen humane tarmmikrobiota.
Ugeskrift for Læger,
180(6), 509-513.
Wray, N. R., Ripke, S.
, Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J.
, Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S.-A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J.
, Buttenschøn, H. N., Bybjerg-Grauholm, J. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2018).
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
Nature Genetics,
50(5), 668-681.
https://doi.org/10.1038/s41588-018-0090-3Anzabi, M., Ardalan, M., Iversen, N. K., H. Rafati, A., Hansen, B. & Østergaard, L. (2018).
Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4.
Frontiers in Cellular Neuroscience,
12(19), Article 19.
Dalsgaard, T., Kaadt, C. R. C., Askou, A. L., Bak, R. O., Andersen, P. O., Hougaard, D.
, Jensen, T. G., Dagnæs-Hansen, F., Mikkelsen, J. G., Corydon, T. J. & Aagaard, L. (2018).
Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein.
Molecular Therapy - Nucleic Acids,
12, 672-683.
https://doi.org/10.1016/j.omtn.2018.07.005
Simonsen, A., Fusaroli, R., Bliksted, V., Mors, O., Roepstorff, A. & Campbell-Meiklejohn, D. (2018).
INTEGRATION OF SENSORY AND SOCIAL INFORMATION DURING DECISION MAKING IN SCHIZOPHRENIA.
Schizophrenia Bulletin,
44(suppl 1), S350-S350.
https://doi.org/10.1093/schbul/sby018.854
Lillethorup, T. P., Glud, A. N., Landeck, N.
, Alstrup, A. K. O., Jakobsen, S., Vang, K., Doudet, D. J., Brooks, D. J., Kirik, D., Hinz, R.
, Sorensen, J. C. & Landau, A. M. (2018).
In vivo quantification of glial activation in minipigs overexpressing human alpha-synuclein.
Synapse,
72(12), Article 22060.
https://doi.org/10.1002/syn.22060
Lillethorup, T. P., GLUD, AN., Alstrup, A. K. O., Noer, O., Nielsen, E. H. T., Schacht, A. C., Landeck, N., Kirik, D.
, Orlowski, D., Sørensen, J. C. H., Doudet, D. J.
& Landau, A. (2018).
Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs.
Scientific Reports,
8(1), Article 15715.
https://doi.org/10.1038/s41598-018-34084-5
Czeh, B.
, Vardya, I., Varga, Z.
, Febbraro, F., Csabai, D.
, Martis, L.-S., Højgaard, K., Henningsen, K., Bouzinova, E., Miseta, A.
, Jensen, K. & Wiborg, O. (2018).
Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats.
Frontiers in Cellular Neuroscience,
12, Article 148.
https://doi.org/10.3389/fncel.2018.00148Bannach-Brown, A., Przybyła, P., Thomas, J., Rice, A. S. C., Ananiadou, S., Liao, J. & Macleod, M. R. (2018).
Machine learning algorithms for systematic reviews: reducing workload in a preclinical review of animal studies and reducing human screening error. bioRxiv.
http://biorxiv.org/content/early/2018/10/30/255760.abstract
Viuff, A. C., Sharp, G. C., Rai, D.
, Henriksen, T. B., Pedersen, L. H., Kyng, K. J., Staunstrup, N. H., Cortes, A.
, Neumann, A., Felix, J. F., Tiemeier, H., Jaddoe, V. W. V. & Relton, C. L. (2018).
Maternal depression during pregnancy and cord blood DNA methylation: findings from the Avon Longitudinal Study of Parents and Children.
Translational Psychiatry,
8(1), Article 244.
https://doi.org/10.1038/s41398-018-0286-4
Winther, G., Elfving, B., Müller, H. K., Lund, S. & Wegener, G. (2018).
Maternal High-fat Diet Programs Offspring Emotional Behavior in Adulthood.
Neuroscience,
388, 87-101.
https://doi.org/10.1016/j.neuroscience.2018.07.014
Lisboa, S. F., Issy, A. C., Biojone, C., Montezuma, K., Fattori, V., Del-Bel, E. A., Guimarães, F. S., Cunha, F. Q., Verri, W. A.
& Joca, S. R. L. (2018).
Mice lacking interleukin-18 gene display behavioral changes in animal models of psychiatric disorders: Possible involvement of immunological mechanisms.
Journal of Neuroimmunology,
314, 58-66.
https://doi.org/10.1016/j.jneuroim.2017.11.008Lisboa, S. F. S., Issy, A. C.
, Biojone, C., Montezuma, K., Fattori, V., Del-Bel, E. A., Guimaraes, F. S., Cunha, F. Q., Verri, W. A.
& Joca, S. R. L. (2018).
Mice lacking interleukin-18 gene display behavioral changes in animal models of psychiatric disorders: Possible involvement of immunological mechanisms.
Journal of Neuroimmunology.
Chen, F., Ardalan, M., Elfving, B., Wegener, G., M Madsen, T.
& Nyengaard, J. R. (2018).
Mitochondria are critical for BDNF-mediated Synaptic and Vascular plasticity of Hippocampus following Repeated Electroconvulsive Seizures.
International Journal of Neuropsychopharmacology,
21(3), 291-304.
https://doi.org/10.1093/ijnp/pyx115
Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W.
, Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M. ... Lewis, C. M. (2018).
New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation.
The Pharmacogenomics Journal,
18(3), 413-421.
https://doi.org/10.1038/tpj.2017.44Lillethorup, T. P., Glud, A. N., Alstrup, A. K. O., Mikkelsen, T. W., Nielsen, E. H. T., Zaer, H., Doudet, D. J.
, Brooks, D. J., Sørensen, J. C. H., Orlowski, D. & Landau, A. M. (2018).
Nigrostriatal proteasome inhibition impairs dopamine neurotransmission and motor function in minipigs.
Experimental Neurology,
303, 142-152.
https://doi.org/10.1016/j.expneurol.2018.02.005