Publications 2018

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Liebenberg, N., Jensen, E., Larsen, E. R., Kousholt, B. S., Pereira, V. S., Fischer, C. W. & Wegener, G. (2018). A Preclinical Study of Casein Glycomacropeptide as a Dietary Intervention for Acute Mania. International Journal of Neuropsychopharmacology, 21(5), 473-484. https://doi.org/10.1093/ijnp/pyy012

Pereira, V. S. & Hiroaki-Sato, V. A. (2018). A brief history of antidepressant drug development: From tricyclics to beyond ketamine. Acta Neuropsychiatrica, 30(6), 307-322. https://doi.org/10.1017/neu.2017.39

Chen, F., Danladi, J., Ardalan, M., Elfving, B., Müller, H. K., Wegener, G., Sanchez, C. & Nyengaard, J. R. (2018). A critical role of mitochondria in BDNF-associated synaptic plasticity after one-week vortioxetine treatment. International Journal of Neuropsychopharmacology, 21(6), 603-615. https://doi.org/10.1093/ijnp/pyy022

Zeppelin, T., Ladefoged, L. K., Sinning, S., Periole, X. & Schiøtt, B. (2018). A direct interaction of cholesterol with the dopamine transporter prevents its out-to-inward transition. PLOS Computational Biology, 14(1), [e1005907]. https://doi.org/10.1371/journal.pcbi.1005907

Bertelsen, F., Landau, A. M., Vase, K. H., Jacobsen, J., Scheel-Krüger, J. & Møller, A. (2018). Acute in vivo effect of valproic acid on the GABAergic system in rat brain: A [C-11]Ro15-4513 microPET study. Brain Research, 1680, 110-114. https://doi.org/10.1016/j.brainres.2017.12.018

Sales, A. J. & Joca, S. R. L. (2018). Antidepressant administration modulates stress-induced DNA methylation and DNA methyltransferase expression in rat prefrontal cortex and hippocampus. Behavioural Brain Research, 343, 8-15. https://doi.org/10.1016/j.bbr.2018.01.022

Sales, A. J., Crestani, C. C., Guimarães, F. S. & Joca, S. R. L. (2018). Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 86, 255-261. https://doi.org/10.1016/j.pnpbp.2018.06.002

de Jong, S., Diniz, M. J. A., Saloma, A., Gadelha, A., Santoro, M. L., Ota, V. K., Noto, C., Curtis, C., Newhouse, S. J., Patel, H., Hall, L. S., O Reilly, P. F., Belangero, S. I., Bressan, R. A., Breen, G. & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (Per Qvist and Preben Bo Mortensen, members of-) (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1, [163]. https://doi.org/10.1038/s42003-018-0155-y

Diniz, C. R. A. F., Casarotto, P. C., Resstel, L. & Joca, S. R. L. (2018). Beyond good and evil: A putative continuum-sorting hypothesis for the functional role of proBDNF/BDNF-propeptide/mBDNF in antidepressant treatment. Neuroscience & Biobehavioral Reviews, 90, 70-83. https://doi.org/10.1016/j.neubiorev.2018.04.001

Déziel, R. A. & Tasker, R. A. (2018). Bilateral ischaemic lesions of the medial prefrontal cortex are anxiogenic in the rat. Acta Neuropsychiatrica, 30(3), 181-186. https://doi.org/10.1017/neu.2017.32

Kaadt, E., Mumm, B. H., Andersen, S. N., Damgaard, C. K. & Elfving, B. (2018). Biomarkers of depression in skin - a novel approach. 1:1-23 (page 15). Abstract from SCNP - 2018, Aarhus.

Qvist, P., Eskildsen, S. F., Hansen, B., Baragji, M., Ringgaard, S., Roovers, J., Paternoster, V., Molgaard, S., Corydon, T. J., Stødkilde-Jørgensen, H., Glerup, S., Mors, O., Wegener, G., Nyengaard, J. R., Børglum, A. D. & Christensen, J. H. (2018). Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/- mice. Scientific Reports, 8(1), 16486. https://doi.org/10.1038/s41598-018-34729-5

Laursen, L., Kristensen, K. B., Periole, X., Overby, M., Müller, H. K., Schiøtt, B. & Sinning, S. (2018). Cholesterol binding to a conserved site modulates conformation, pharmacology and transport kinetics of the human serotonin transporter. Journal of Biological Chemistry, 293(10), 3510-3523. https://doi.org/10.1074/jbc.M117.809046

van der Kooij, M. A., Jene, T., Treccani, G., Miederer, I., Hasch, A., Voelxen, N., Walenta, S. & Müller, M. B. (2018). Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory. Proceedings of the National Academy of Sciences of the United States of America, 115(43), E10187-E10196. https://doi.org/10.1073/pnas.1804412115

Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. A. F., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A., Baune, B. T. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2018). Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium. Biological Psychiatry, 84(2), 138-147. https://doi.org/10.1016/j.biopsych.2017.09.009

Winther, G. (2018). Early Life Programming of Brain and Behaviour.

Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S-H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M. ... Lewis, C. M. (2018). Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 28(8), 945-954. https://doi.org/10.1016/j.euroneuro.2018.05.009

Happ, D. F. & Tasker, R. A. (2018). Effects of α7 Nicotinic Receptor Activation on Cell Survival in Rat Organotypic Hippocampal Slice Cultures. Neurotoxicity Research, 33(4), 887-895. https://doi.org/10.1007/s12640-017-9854-2

Landau, A. M., Alstrup, A. K. O., Audrain, H., Jakobsen, S., Simonsen, M., Møller, A., Videbech, P. B., Wegener, G., Gjedde, A. & Doudet, D. J. (2018). Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy. Journal of Cerebral Blood Flow and Metabolism, 38(5), 881-887. https://doi.org/10.1177/0271678X17705260

Severino, M., Sivasaravanaparan, M., Olesen, L., von Linstow, C. U., Metaxas, A., Bouzinova, E. V., Khan, A. M., Lambertsen, K. L., Babcock, A. A., Gramsbergen, J. B., Wiborg, O. & Finsen, B. (2018). Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 4, 215-223. https://doi.org/10.1016/j.trci.2018.04.005

Wang, Q., Liao, J., Hair, K., Bannach-Brown, A., Bahor, Z., Currie, G. L., McCann, S. K., Howells, D. W., Sena, E. S. & Macleod, M. R. (2018). Estimating the statistical performance of different approaches to meta-analysis of data from animal studies in identifying the impact of aspects of study design. bioRxiv. http://biorxiv.org/content/early/2018/01/30/256776.abstract

Bak, S. T., Staunstrup, N. H., Starnawska, A., Daugaard, T. F., Nyengaard, J. R., Nyegaard, M., Børglum, A., Mors, O., Dorph-Petersen, K-A. & Nielsen, A. L. (2018). Evaluating the Feasibility of DNA Methylation Analyses Using Long-Term Archived Brain Formalin-Fixed Paraffin-Embedded Samples. Molecular Neurobiology, 55(1), 668-681. https://doi.org/10.1007/s12035-016-0345-x

Al-Absi, A. R., Christensen, H. S., Sanchez, C. & Nyengaard, J. R. (2018). Evaluation of semi-automatic 3D reconstruction for studying geometry of dendritic spines. Journal of Chemical Neuroanatomy, 94, 119-124. https://doi.org/10.1016/j.jchemneu.2018.10.008

Buttenschøn, H. N., Elfving, B., Nielsen, M., Skeldal, S., Kaas, M., Mors, O. & Glerup, S. (2018). Exploring the sortilin related receptor, SorLA, in depression. Journal of Affective Disorders, 232, 260-267. https://doi.org/10.1016/j.jad.2018.02.050

Masana, M., Westerholz, S., Kretzschmar, A., Treccani, G., Liebl, C., Santarelli, S., Dournes, C., Popoli, M., Schmidt, M. V., Rein, T. & Müller, M. B. (2018). Expression and glucocorticoid-dependent regulation of the stress-inducible protein DRR1 in the mouse adult brain. Brain Structure and Function (Print Edition), 223(9), 4039–4052. https://doi.org/10.1007/s00429-018-1737-7

Roberts, D., Wolfarth, A., Sanchez, C. & Pehrson, A. L. (2018). Frontal cortex dysfunction as a target for remediation in opiate use disorder: Role in cognitive dysfunction and disordered reward systems. In S. O'Mara (Ed.), The Opioid System as the Interface between the Brain’s Cognitive and Motivational Systems (Vol. 239, pp. 179-227). Elsevier. Progress in Brain Research Vol. 239 https://doi.org/10.1016/bs.pbr.2018.07.001

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S-A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics, 50(5), 668-681. https://doi.org/10.1038/s41588-018-0090-3

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2018). Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. PLOS ONE, 13(12), [e0209160]. https://doi.org/10.1371/journal.pone.0209160

Anzabi, M., Ardalan, M., Iversen, N. K., H. Rafati, A., Hansen, B. & Østergaard, L. (2018). Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4. Frontiers in Cellular Neuroscience, 12(19).

Sartim, A. G., Sales, A. J., Guimarães, F. S. & Joca, S. R. (2018). Hippocampal mammalian target of rapamycin is implicated in stress-coping behavior induced by cannabidiol in the forced swim test. Journal of Psychopharmacology, 32(8), 922-931. https://doi.org/10.1177/0269881118784877

Simonsen, A., Fusaroli, R., Bliksted, V., Mors, O., Roepstorff, A. & Campbell-Meiklejohn, D. (2018). INTEGRATION OF SENSORY AND SOCIAL INFORMATION DURING DECISION MAKING IN SCHIZOPHRENIA. Schizophrenia Bulletin, 44(suppl 1), S350-S350. https://doi.org/10.1093/schbul/sby018.854

Tillmann, S. (2018). Impact of gut microbiota modulation on host behavior and metabolism.

Dalsgaard, T., Kaadt, C. R. C., Askou, A. L., Bak, R. O., Andersen, P. O., Hougaard, D., Jensen, T. G., Dagnæs-Hansen, F., Mikkelsen, J. G., Corydon, T. J. & Aagaard, L. (2018). Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein. Molecular Therapy - Nucleic Acids, 12, 672-683. https://doi.org/10.1016/j.omtn.2018.07.005

Lillethorup, T. P., Glud, A. N., Landeck, N., Alstrup, A. K. O., Jakobsen, S., Vang, K., Doudet, D. J., Brooks, D. J., Kirik, D., Hinz, R., Sorensen, J. C. & Landau, A. M. (2018). In vivo quantification of glial activation in minipigs overexpressing human alpha-synuclein. Synapse, 72(12), [22060]. https://doi.org/10.1002/syn.22060

Buttenschøn, H. N., Nielsen, M., Glerup, S. & Mors, O. (2018). Investigation of serum levels of sortilin in response to antidepressant treatment. Acta Neuropsychiatrica, 30(2), 111-116. https://doi.org/10.1017/neu.2017.13

Christensen, K. & Bertelsen, A. (2018). Irving I. Gottesman's Collaboration in Psychiatric Genetics Research in Denmark. Twin Research and Human Genetics, 21(4), 322-323. https://doi.org/10.1017/thg.2018.32

Czeh, B., Vardya, I., Varga, Z., Febbraro, F., Csabai, D., Martis, L-S., Højgaard, K., Henningsen, K., Bouzinova, E., Miseta, A., Jensen, K. & Wiborg, O. (2018). Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats. Frontiers in Cellular Neuroscience, 12, [148]. https://doi.org/10.3389/fncel.2018.00148

Lillethorup, T. P., GLUD, AN., Alstrup, A. K. O., Noer, O., Nielsen, E. H. T., Schacht, A. C., Landeck, N., Kirik, D., Orlowski, D., Sørensen, J. C. H., Doudet, D. J. & Landau, A. (2018). Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs. Scientific Reports, 8, [15715]. https://doi.org/10.1038/s41598-018-34084-5

Bannach-Brown, A., Przybyła, P., Thomas, J., Rice, A. S. C., Ananiadou, S., Liao, J. & Macleod, M. R. (2018). Machine learning algorithms for systematic reviews: reducing workload in a preclinical review of animal studies and reducing human screening error. bioRxiv. http://biorxiv.org/content/early/2018/10/30/255760.abstract

Winther, G., Elfving, B., Müller, H. K., Lund, S. & Wegener, G. (2018). Maternal High-fat Diet Programs Offspring Emotional Behavior in Adulthood. Neuroscience, 388, 87-101. https://doi.org/10.1016/j.neuroscience.2018.07.014

Viuff, A. C., Sharp, G. C., Rai, D., Henriksen, T. B., Pedersen, L. H., Kyng, K. J., Staunstrup, N. H., Cortes, A., Neumann, A., Felix, J. F., Tiemeier, H., Jaddoe, V. W. V. & Relton, C. L. (2018). Maternal depression during pregnancy and cord blood DNA methylation: findings from the Avon Longitudinal Study of Parents and Children. Translational Psychiatry, 8, [244]. https://doi.org/10.1038/s41398-018-0286-4

Lisboa, S. F., Issy, A. C., Biojone, C., Montezuma, K., Fattori, V., Del-Bel, E. A., Guimarães, F. S., Cunha, F. Q., Verri, W. A. & Joca, S. R. L. (2018). Mice lacking interleukin-18 gene display behavioral changes in animal models of psychiatric disorders: Possible involvement of immunological mechanisms. Journal of Neuroimmunology, 314, 58-66. https://doi.org/10.1016/j.jneuroim.2017.11.008

Tillmann, S. (2018). Mind the gap – towards complete and transparent reporting of animal research. Medical Writing, 26(4), 24-27. http://journal.emwa.org/preclinical-studies/mind-the-gap-towards-complete-and-transparent-reporting-of-animal-research/

Chen, F., Ardalan, M., Elfving, B., Wegener, G., M Madsen, T. & Nyengaard, J. R. (2018). Mitochondria are critical for BDNF-mediated Synaptic and Vascular plasticity of Hippocampus following Repeated Electroconvulsive Seizures. International Journal of Neuropsychopharmacology, 21(3), 291-304. https://doi.org/10.1093/ijnp/pyx115

Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M. ... Lewis, C. M. (2018). New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation. The Pharmacogenomics Journal, 18(3), 413-421. https://doi.org/10.1038/tpj.2017.44

Lillethorup, T. P., Glud, A. N., Alstrup, A. K. O., Mikkelsen, T. W., Nielsen, E. H. T., Zaer, H., Doudet, D. J., Brooks, D. J., Sørensen, J. C. H., Orlowski, D. & Landau, A. M. (2018). Nigrostriatal proteasome inhibition impairs dopamine neurotransmission and motor function in minipigs. Experimental Neurology, 303, 142-152. https://doi.org/10.1016/j.expneurol.2018.02.005

Bay, V. (2018). Novel approaches to modeling pre-stroke depression in the rat.

Alstrup, A. K. O., Munk, O. L., Landau, A. M. & Lillethorup, T. P. (2018). PET radioligand injection for pig neuroimaging. Scandinavian Journal of Laboratory Animal Science, 44(2), 1-5.

Pedersen, K., Bertelsen, A. & Mors, O. (Ed.) (2018). Present State Examination: Kort version til klinisk brug. (5 ed.) Munksgaard .

Abildgaard, A., Elfving, B., Müller, H. K., Hokland, M., Lund, S. & Wegener, G. (2018). Probiotics - a novel antidepressant? Lessons from preclinical studies. 11-12. Abstract from SCNP 59th Annual Meeting 2018, Aarhus, Denmark.

Displaying results 1 to 50 out of 70

Revised 31.01.2023

Karen Jul Madsen