Publications from TNU
Arjmand, S., Rezaei, M., Sardella, D., Cecchi, C. R., Rossi, R., Vægter, C. B., Müller, H. K., Sahana, J., Nielsen, M. S., Landau, A. M., Simonsen, U., Sinning, S., Wegener, G., Joca, S. & Biojone, C. (2026). Antidepressants interact with sex steroid receptors and their intracellular signaling components. bioRxiv. https://doi.org/10.64898/2026.03.17.712321
Arjmand, S., Chaudhary, M., Samudyata, Piehl, F., Pelanis, A., Engberg, G., Cervenka, S., Landén, M., Erhardt, S. & Sellgren, C. M. (2026). Divergence of C4A and C4B in first-episode psychosis: Insights from CSF and plasma immune profiling. Translational Psychiatry, 16(1), Article 236. https://doi.org/10.1038/s41398-026-04037-y
Arjmand, S. & Sellgren, C. M. (2026). How Soon Is Now? Biological Psychiatry Global Open Science, 6(3), Article 100708. https://doi.org/10.1016/j.bpsgos.2026.100708
Azizi, F., Chan, W. K. & Ardalan, M. (2026). Aquaporins: Bridging Normal Brain Development and Neurodevelopmental Disorder Mechanisms. Developmental Neuroscience, 48(2), 115-129. https://doi.org/10.1159/000545512
Best Jensen, R., Kjølhede, M., Just, J., Clegg, L.-A., Baek, R., Kaadt, E., Elfving, B., Hess, D. C., Andersen, G., Jørgensen, M. M., Blauenfeldt, R. A. & Drasbek, K. R. (2026). Exploring extracellular vesicle surface markers and microRNA regulation following remote ischemic conditioning in patients with stroke: a randomized-controlled pilot study. BMC Neuroscience, 27(1), Article 10. https://doi.org/10.1186/s12868-025-00993-1
Bittencourt, A. M. L., Favero, B. P., Haas, C., Portolan, E. T., Gallardo, E., Rothmann, L. M., Grassi-Oliveira, R. & Viola, T. W. (2026). Patterns of structural brain differences in cocaine use disorder: Integrating multilevel frequentist, Bayesian, and coordinate-based meta-analyses. Drug and Alcohol Dependence, 281, Article 113064. https://doi.org/10.1016/j.drugalcdep.2026.113064
Bojesen, K. B., Ambrosen, K. S., Sigvard, A. K., Nielsen, M. Ø., Gjedde, A., Kumakura, Y., Jensen, L. T., Fuglø, D., Ebdrup, B. H., Rostrup, E. & Glenthøj, B. Y. (2026). Interrelations between dopaminergic-, gabaergic- and glutamatergic neurotransmitters in antipsychotic-naïve psychosis patients and the association to initial treatment response. Molecular Psychiatry, 31(3), 1231-1240. https://doi.org/10.1038/s41380-025-03229-0
Buchholtz, P. E. (2026). Lavfrekvent repetitiv transkraniel magnetisk stimulation mod depression. Ugeskrift for Læger, 188(4), 1-8. https://doi.org/10.61409/V06250521
Chan, W. K., Jabbari Shiadeh, S. M., Lenzig, J., Svedin, P., Rasmusson, S., Vigne, O., Veit, V., Chumak, T., Ardalan, M. & Mallard, C. (2026). Immune Synaptopathy and Sex Differences in Recognition Memory from Neonatal Staphylococcus epidermidis Infection. Developmental Neuroscience, 1-25. Advance online publication. https://doi.org/10.1159/000548381
Chan, W. K., Rasmusson, S., Shiadeh, S. M. J., Wilhelmsson, R., Johansson, M. E., Elfving, B., Müller, H. K., Mallard, C. & Ardalan, M. (2026). The Role of Serotonin in Brain Development: From Molecular Pathways to Neurodevelopmental Risk. Cellular and Molecular Neurobiology, 46(1), Article 89. https://doi.org/10.1007/s10571-026-01746-2
Dahlaki, M. H., Alam, M. Z. B., Nielsen, M. N., Buttenschøn, H. N. & Winterdahl, M. (2026). Age-Dependent Increase in Peripheral Neuropeptide Y with No Cross-Sectional Link to Depression. Acta Neuropsychiatrica. Advance online publication. https://doi.org/10.1017/neu.2026.10084
de Mattos, B. P., Mattjie, C., Ravazio, R., Barros, R. C. & Grassi-Oliveira, R. (2026). Craving for a Robust Methodology: A Systematic Review of Machine Learning Algorithms on Substance-Use Disorders Treatment Outcomes. International Journal of Mental Health and Addiction, 24(2), 1090-1117. https://doi.org/10.1007/s11469-024-01403-z
Egorova, O., Domellöf, E., Ardalan, M. & Mallard, C. (2026). Folate Receptor Alpha (FRα) and the Developing Brain: From Molecular Function to Neurodevelopmental Outcomes. Molecular Neurobiology, 63(1), Article 522. https://doi.org/10.1007/s12035-026-05813-z
Faddy, E., Johansen, M. I., Gadeberg, C., Meyer, R. L., Østergaard, L., Bay-Richter, C., Jensen, L. K., Vendelbo, M. H. & Jørgensen, N. P. (2026). [18F]Fluorodeoxyglucose Positron Emission Tomography for diagnosis and monitoring of acute Staphylococcus aureus vascular graft infection in a rat model. The Journal of Infectious Diseases, 233(2), e332-e341. Article jiaf594. https://doi.org/10.1093/infdis/jiaf594
Garcia, M. G., Baldi, B. B. C., Giuberti, P., Chrusciel, J. H., Berlaver, S. T., Machado, G. C., Lodi, M. A., Kristensen, C. H., Tractenberg, S. G., Grassi-Oliveira, R. & Viola, T. W. (2026). Translation, Cross-Cultural Adaptation, and Validation of the Storm Fear Questionnaire in Brazilian Pregnant Women Exposed to an Extreme Climate Event. Brain Sciences, 16(3), Article 288. https://doi.org/10.3390/brainsci16030288
Gobira, P. H., Bastos, S., Rossi, R., Vægter, C. B., Chen, F., da Silva, N. R., Müller, H. K., Joca, S., Boesen, T., Viola, T. W., Yan, Y., Larsen, M. R., Carregar, V. C. & Grassi-Oliveira, R. (2026). Morphine reprograms brain-derived extracellular vesicle cargo associated with synaptic remodeling in the prefrontal cortex. Neurobiology of Disease, 107501. Advance online publication. https://doi.org/10.1016/j.nbd.2026.107501
Leal, J. A. V., Souza, M. S., Viola, T. W. & Grassi-Oliveira, R. (2026). Increased risk of depression and suicidal behavior associated with pesticide exposure: A systematic review and multilevel meta-analysis. Journal of Affective Disorders Reports, 25, Article 101091. https://doi.org/10.1016/j.jadr.2026.101091
Marsh, W. A., Scarsbrook, L., Yüncü, E., Hodgson, L., Lin, A. T., De Iorio, M., Thalmann, O., Thomas, M. G., Goor, M., Bergström, A., Noseda, A., Amiri, S., Biglari, F., Borić, D., Bougiouri, K., Carmagnini, A., Giannì, M., Higham, T., Lebrasseur, O. ... Frantz, L. A. F. (2026). Dogs were widely distributed across western Eurasia during the Palaeolithic. Nature, 651(8107), 995-1003. https://doi.org/10.1038/s41586-026-10170-x
Schuurmans, I. K., Mulder, R. H., Baltramonaityte, V., Lahtinen, A., Qiuyu, F., Rothmann, L. M., Staginnus, M., Tuulari, J. J., Burt, S. A., Buss, C., Craig, J. M., Donald, K. A., Eriksson, J. G., Felix, J. F., Freeman, T. P., Grassi-Oliveira, R., Huels, A., Hyde, L. W., Jones, S. A. ... Cecil, C. A. M. (2026). Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium. Molecular Psychiatry, 31(2), 1177-1189. https://doi.org/10.1038/s41380-025-03203-w
Seijas-Pedroza, G., Del Val, A. G., Wegener, G., Simonsen, U. & Comerma-Steffensen, S. (2026). Impact of a non-invasive oestrous synchronisation protocol on sexual behaviour in Sprague-Dawley rats. Journal of Sexual Medicine, 23(7). https://doi.org/10.1093/jsxmed/qdag164
Skriver, S. A., Arjmand, S., Andersen, A. B., Wegener, G. & Hansen, M. (2026). A single S-ketamine injection enhances mTOR signaling in rat skeletal muscle. Journal of Muscle Research and Cell Motility, 47(1), Article 1. https://doi.org/10.1007/s10974-025-09720-z
Wegener, G., Lerer, B., Frazer, A., Grace, A., Ikeda, K., Gobbi, G., Young, A., Zohar, J., Blier, P., Kasper, S., Krystal, J., Yamawaki, S., Philips, A., Möller, H. J., Belmaker, R. H., Atwoli, L., Nutt, D., Harvey, B. H., Seedat, S. ... Emsley, R. (2026). In memoriam: Professor Dan J. Stein (1962-2025) — a global pioneer with an African heart. International Journal of Neuropsychopharmacology, 29(1), Article pyaf079. https://doi.org/10.1093/ijnp/pyaf079
Andersen, J. V., Aldana, B. I., Bak, L. K., Behar, K. L., Borges, K., Carruthers, A., Cumming, P., Derouiche, A., Díaz-García, C. M., Drew, K. L., Duarte, J. M. N., Ferreira, G. C., Giove, F., Gjedde, A., Hyder, F., Ioannou, M. S., Kann, O., Kristian, T., Lai, J. C. K. ... McKenna, M. C. (2025). Embracing Scientific Debate in Brain Metabolism. Journal of Neurochemistry, 169(9), Article e70230. https://doi.org/10.1111/jnc.70230
Anzalone, M., Karam, S. A., Briting, S. R. R., Petersen, S., Thomsen, M. B., Babcock, A. A., Landau, A. M., Finsen, B. & Metaxas, A. (2025). Serotonin-2B receptor (5-HT2BR) expression and binding in the brain of APPswe/PS1dE9 transgenic mice and in Alzheimer's disease brain tissue. Neuroscience Letters, 844, Article 138013. https://doi.org/10.1016/j.neulet.2024.138013
Arjmand, S., Ilaghi, M., Shafie’ei, M., Gobira, P., Grassi-Oliveira, R. & Wegener, G. (2025). Exploring the potential link between ΔFosB and N-acetylcysteine in craving/relapse dynamics: can N-acetylcysteine stand out as a possible treatment candidate? Acta Neuropsychiatrica, 37, 1-14. Article e31. https://doi.org/10.1017/neu.2024.38
Arjmand, S., Lindström, M. B., Sellgren, C. M. & Wegener, G. (2025). Sleep-administered ketamine/psychedelics: A streamlined strategy to address two challenges in research on ketamine and psychedelics. European psychiatry : the journal of the Association of European Psychiatrists, 68(1), 1-5. Article e29. https://doi.org/10.1192/j.eurpsy.2025.14
Bay-Richter, C., Silseth, E. K. K., Genovese, E., Kvorning, A., Whitehead, B., Nejsum, P. L. & Wegener, G. (2025). A Macrobiotic Treatment Approach to Alleviate ‘Chemo-brain’ and Chemotherapy-induced Sickness. Poster session presented at PNIRS Annual Meeting 2025, Bordeaux, France.
HappyMums Consortium (2025). Understanding, predicting, and treating depression in pregnancy to improve mothers' and offspring's mental health outcomes: The HappyMums study. Brain, Behavior, and Immunity - Health, 44, Article 100961. https://doi.org/10.1016/j.bbih.2025.100961
Binda, K. H., Real, C. C., Simonsen, M. T., Grove, E. K., Bender, D., Gjedde, A., Brooks, D. J. & Landau, A. M. (2025). Acute transcutaneous auricular vagus nerve stimulation modulates presynaptic SV2A density in healthy rat brain: An in vivo microPET study. Psychophysiology, 62(1), Article e14709. https://doi.org/10.1111/psyp.14709
Brandão-Teles, C., Carregari, V. C., Reis-de-Oliveira, G., Smith, B. J., Chaves, Y., Sousa Santos, A. V., Pinheiro, E. M. D. C., Oliveira, C. C., Vieira, A. S., Crunfli, F. & Martins-de-Souza, D. (2025). Impacts of hnRNP A1 Splicing Inhibition on the Brain Remyelination Proteome. Journal of Neurochemistry, 169(1), Article e16304. https://doi.org/10.1111/jnc.16304
Brandão-Teles, C., Zuccoli, G. S., Ganzella, M., Corasolla Carregari, V., Olsthoorn, L., de Almeida Duque, É., Munhoz, C. D., Jahn, R., Martins-de-Souza, D. & Crunfli, F. (2025). Isolating Synaptic Vesicles from Neurospheres for Proteomics. Methods in Molecular Biology, 207-223. https://doi.org/10.1007/978-1-0716-4298-6_14
D’Aprile, I., Petrillo, G., Begni, V., Creutzberg, K. C., Orso, R., Grassi-Oliveira, R., Riva, M. A. & Cattaneo, A. (2025). Inflammatory status along the brain-liver axis in animals vulnerable to prenatal stress: sex-related implications for stress-induced comorbidities. Translational Psychiatry, 15(1), Article 392. https://doi.org/10.1038/s41398-025-03622-x
Diniz, C. R. A. F., Crestani, A. P., C Casarotto, P., Biojone, C., Cannarozzo, C., Winkel, F., Prozorov, M. A., Kot, E. F., Goncharuk, S. A., Benette Marques, D., Zacharias, L. R., Autio, H., Pryiadrashini Sahu, M., Borges-Assis, A. B., Pereira Leite, J., Mineev, K. S., Castren, E. & Resstel, L. B. M. (2025). Fluoxetine and Ketamine Enhance Extinction Memory and Brain Plasticity by Triggering the p75 Neurotrophin Receptor Proteolytic Pathway. Biological Psychiatry, 97(3), 248-260. https://doi.org/10.1016/j.biopsych.2024.06.021
Godoy, L. D. & Wegener, G. (2025). Acta Neuropsychiatrica embraces full open access: towards a new era of global knowledge sharing. Acta Neuropsychiatrica, 37, e2. Article e2. https://doi.org/10.1017/neu.2024.66
H.Rafati, A., Rasmusson, S., Marziyeh Jabbari Shiadeh, S., Rosario, F. J., Jansson, T., Mallard, C. & Ardalan, M. (2025). A Novel Framework for Quantitative Analysis of Neuronal Primary Cilia in Brain Tissue.
Jabbari Shiadeh, S. M., Chan, W. K., Rasmusson, S., Hassan, N., Joca, S., Westberg, L., Elfvin, A., Mallard, C. & Ardalan, M. (2025). Bidirectional crosstalk between the gut microbiota and cellular compartments of brain: Implications for neurodevelopmental and neuropsychiatric disorders. Translational Psychiatry, 15(1), Article 278. https://doi.org/10.1038/s41398-025-03504-2
Jakobsen, E. M., Alam, M. Z. B. & Winterdahl, M. (2025). Exploring the link between the use of oral contraceptives and intrauterine devices, and alcohol consumption in young Danish women. Maturitas, 199, Article 108643. https://doi.org/10.1016/j.maturitas.2025.108643
Jensen, N. J., Porse, A. J., Wodschow, H. Z., Speyer, H., Krogh, J., Marner, L., Gejl, M., Gjedde, A. & Rungby, J. (2025). Relation of Insulin Resistance to Brain Glucose Metabolism in Fasting and Hyperinsulinemic States: A Systematic Review and Meta-analysis. Journal of Clinical Endocrinology and Metabolism, 110(2), e525-e537. https://doi.org/10.1210/clinem/dgae570
Jensen, A. A., Cecchi, C. R., Hibicke, M., Bach, A. H., Kaadt, E., Märcher-Rørsted, E., Nichols, C. D., Elfving, B. & Kristensen, J. L. (2025). The Selective Serotonin 5-HT2A Receptor Agonist (S)-3-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)piperidine (LPH-5) Induces Persistent and Robust Antidepressant-Like Effects in Rodents. ACS Pharmacology and Translational Science, 8(6), 1791-1803. https://doi.org/10.1021/acsptsci.5c00208
Joca, S. (2025). Neurodegenerative disorders: Advances in neurobiology and new treatment perspectives. Basic and Clinical Pharmacology and Toxicology, 136(1), Article e14098. https://doi.org/10.1111/bcpt.14098
Johannessen, K., Braný, D., Dvorská, D., Krivošová, M., Oppa, M., Ondrejka, I., Strnádel, J., Ferencová, N., Tonhajzerová, I., Danková, Z., Halašová, E., Mokrý, J. & Elfving, B. (2025). Dysregulated miR-1246 and miR-1253 link inflammatory protein markers in plasma to major depressive disorder in female adolescents. Brain, Behavior, and Immunity - Health, 49, Article 101108. https://doi.org/10.1016/j.bbih.2025.101108
Kai, L. M., Parada Iglesias, L., Kõiv, K., Harro, J. & Wegener, G. (2025). Ultrasonic vocalisations in the Flinders Sensitive Line rat, a genetic animal model of depression. Acta Neuropsychiatrica, 37, Article e3. https://doi.org/10.1017/neu.2024.61
Karsberg, S. H., Thylstrup, B., Thomsen, K. R., Grassi-Oliveira, R., Pedersen, M. M. & Hesse, M. (2025). The Impact of Severe Trauma Exposure in Late Childhood on Longitudinal Treatment Outcomes in Adolescents and Young Adults in Treatment for Drug Use Disorders: A Record-Linkage Study. International Journal of Mental Health and Addiction, 23(2), 1518–1542. https://doi.org/10.1007/s11469-023-01182-z
Knudsen, C., Thomsen, M. B., Højgaard, K., Christiansen, S. L., Wiborg, O., Müller, H. K., Landau, A. M. & Elfving, B. (2025). Agomelatine normalizes region-specific, diurnal mGluR5 dysregulation in a chronic mild stress rat model of depression. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 143, Article 111572. https://doi.org/10.1016/j.pnpbp.2025.111572
Kølbæk, P., Jensen, B. D., Larsen, E. R. & Østergaard, S. D. (2025). Improving the Accuracy and Reliability of Ratings on the Hamilton Depression Rating Scale via a Video-Based Training Program. Acta Psychiatrica Scandinavica, 152(6), 462-472. https://doi.org/10.1111/acps.70029
Krieger, K., Pyka, T., Mingels, C., Sari, H., Gjedde, A., Rominger, A. & Cumming, P. (2025). Kinetics of the amino acid uptake tracer O-(2-[18F]fluoroethyl)-L-tyrosine (FET) in human brain. EJNMMI Research, 15(1), Article 90. https://doi.org/10.1186/s13550-025-01279-7
Krogsbaek, M., Larsen, N. Y., Yarmahmoudi, F., Søndergaard, J., Landau, A. M., Sanchez, C. & Nyengaard, J. R. (2025). Chronic olanzapine treatment leads to increased opioid receptor expression and changes in feeding regulating neurons in the female rat hypothalamus. Psychoneuroendocrinology, 171, Article 107225. https://doi.org/10.1016/j.psyneuen.2024.107225
Landau, A. (2025). Novel Imaging Biomarkers for Brain PET Imaging. Biomolecules, 15(4), 517. Article 517. https://doi.org/10.3390/biom15040517
Malhi, G. S., Bell, E., Szymaniak, K., Looi, J. C. L., Fernandez-Egea, E. & Wegener, G. (2025). Subversion of publishing comes to a boil: is it time to lance it? British Journal of Psychiatry, 227(2), 517-518. https://doi.org/10.1192/bjp.2025.10332
Malhi, G. S., Marsh, J., Ongur, D., Cosci, F., Krystal, J. H., Cropsey, K. L., Wegener, G., Redline, S., Pariante, C. M., Hageman, I., Carter, C., Rief, W., Emsley, R., DeLisi, L. E., Cipriani, A., Crespo-Facorro, B., Kisely, S., Yatham, L. N., Looi, J. C. L. ... Dazzan, P. (2025). Truthful communication of mental science: pledge to our patients and profession. British Journal of Psychiatry, 226(5), 253-255. https://doi.org/10.1192/bjp.2025.94
