Successful Use of Long-term Stored Human Brain Samples for In Situ Hybridization Analysis of Selected microRNAs
In a recent publication, TNU researchers demonstrated that combining Nanostring nCounter technology with miRNAscope analysis offers a robust approach to study the spatial expression of specific microRNAs in human brain samples preserved for up to 76 years in formalin-fixed, paraffin-embedded (FFPE) form.
Read the abstract and perhaps even the full article:
Søkilde, R, Kaadt, E, Kristensen, LS, Venø, MT, Kjems, J, Nyengaard, JR, Nielsen, BS & Elfving, B 2025, 'Application of microRNA In Situ Hybridization on Long-term Stored Human Formalin-fixed Paraffin-embedded Brain Samples from Psychiatric Patients', Molecular Neurobiology. https://doi.org/10.1007/s12035-025-05077-z
Contact
Associate Professor
Betina Elfving
Translational Neuropsychiatry Unit