Publications 2025

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Andersen, J. V., Aldana, B. I., Bak, L. K., Behar, K. L., Borges, K., Carruthers, A., Cumming, P., Derouiche, A., Díaz-García, C. M., Drew, K. L., Duarte, J. M. N., Ferreira, G. C., Giove, F., Gjedde, A., Hyder, F., Ioannou, M. S., Kann, O., Kristian, T., Lai, J. C. K. ... McKenna, M. C. (2025). Embracing Scientific Debate in Brain Metabolism. Journal of Neurochemistry, 169(9), Article e70230. https://doi.org/10.1111/jnc.70230

Anzalone, M., Karam, S. A., Briting, S. R. R., Petersen, S., Thomsen, M. B., Babcock, A. A., Landau, A. M., Finsen, B. & Metaxas, A. (2025). Serotonin-2B receptor (5-HT_2BR) expression and binding in the brain of APP_swe/PS1_dE9 transgenic mice and in Alzheimer's disease brain tissue. Neuroscience Letters, 844, Article 138013. https://doi.org/10.1016/j.neulet.2024.138013

Arjmand, S., Ilaghi, M., Shafie’ei, M., Gobira, P., Grassi-Oliveira, R. & Wegener, G. (2025). Exploring the potential link between ΔFosB and N-acetylcysteine in craving/relapse dynamics: can N-acetylcysteine stand out as a possible treatment candidate? Acta Neuropsychiatrica, 37, 1-14. Article e31. https://doi.org/10.1017/neu.2024.38

Arjmand, S., Lindström, M. B., Sellgren, C. M. & Wegener, G. (2025). Sleep-administered ketamine/psychedelics: A streamlined strategy to address two challenges in research on ketamine and psychedelics. European psychiatry : the journal of the Association of European Psychiatrists, 68(1), 1-5. Article e29. https://doi.org/10.1192/j.eurpsy.2025.14

Azizi, F., Chan, W. K. & Ardalan, M. (2025). Aquaporins: Bridging Normal Brain Development and Neurodevelopmental Disorder Mechanisms. Developmental Neuroscience. Advance online publication. https://doi.org/10.1159/000545512

Bay-Richter, C., Silseth, E. K. K., Genovese, E., Kvorning, A., Whitehead, B., Nejsum, P. L. & Wegener, G. (2025). A Macrobiotic Treatment Approach to Alleviate ‘Chemo-brain’ and Chemotherapy-induced Sickness. Poster session presented at PNIRS Annual Meeting 2025, Bordeaux, France.

HappyMums Consortium (2025). Understanding, predicting, and treating depression in pregnancy to improve mothers' and offspring's mental health outcomes: The HappyMums study. Brain, Behavior, and Immunity - Health, 44, Article 100961. https://doi.org/10.1016/j.bbih.2025.100961

Binda, K. H., Real, C. C., Simonsen, M. T., Grove, E. K., Bender, D., Gjedde, A., Brooks, D. J. & Landau, A. M. (2025). Acute transcutaneous auricular vagus nerve stimulation modulates presynaptic SV2A density in healthy rat brain: An in vivo microPET study. Psychophysiology, 62(1), Article e14709. https://doi.org/10.1111/psyp.14709

Bojesen, K. B., Ambrosen, K. S., Sigvard, A. K., Nielsen, M. Ø., Gjedde, A., Kumakura, Y., Jensen, L. T., Fuglø, D., Ebdrup, B. H., Rostrup, E. & Glenthøj, B. Y. (2025). Interrelations between dopaminergic-, gabaergic- and glutamatergic neurotransmitters in antipsychotic-naïve psychosis patients and the association to initial treatment response. Molecular Psychiatry. Advance online publication. https://doi.org/10.1038/s41380-025-03229-0

Brandão-Teles, C., Carregari, V. C., Reis-de-Oliveira, G., Smith, B. J., Chaves, Y., Sousa Santos, A. V., Pinheiro, E. M. D. C., Oliveira, C. C., Vieira, A. S., Crunfli, F. & Martins-de-Souza, D. (2025). Impacts of hnRNP A1 Splicing Inhibition on the Brain Remyelination Proteome. Journal of Neurochemistry, 169(1), Article e16304. https://doi.org/10.1111/jnc.16304

Brandão-Teles, C., Zuccoli, G. S., Ganzella, M., Corasolla Carregari, V., Olsthoorn, L., de Almeida Duque, É., Munhoz, C. D., Jahn, R., Martins-de-Souza, D. & Crunfli, F. (2025). Isolating Synaptic Vesicles from Neurospheres for Proteomics. Methods in Molecular Biology, 207-223. https://doi.org/10.1007/978-1-0716-4298-6_14

D’Aprile, I., Petrillo, G., Begni, V., Creutzberg, K. C., Orso, R., Grassi-Oliveira, R., Riva, M. A. & Cattaneo, A. (2025). Inflammatory status along the brain-liver axis in animals vulnerable to prenatal stress: sex-related implications for stress-induced comorbidities. Translational Psychiatry, 15(1), Article 392. https://doi.org/10.1038/s41398-025-03622-x

Diniz, C. R. A. F., Crestani, A. P., C Casarotto, P., Biojone, C., Cannarozzo, C., Winkel, F., Prozorov, M. A., Kot, E. F., Goncharuk, S. A., Benette Marques, D., Zacharias, L. R., Autio, H., Pryiadrashini Sahu, M., Borges-Assis, A. B., Pereira Leite, J., Mineev, K. S., Castren, E. & Resstel, L. B. M. (2025). Fluoxetine and Ketamine Enhance Extinction Memory and Brain Plasticity by Triggering the p75 Neurotrophin Receptor Proteolytic Pathway. Biological Psychiatry, 97(3), 248-260. https://doi.org/10.1016/j.biopsych.2024.06.021

Faddy, E., Johansen, M. I., Gadeberg, C., Meyer, R. L., Østergaard, L., Bay-Richter, C., Jensen, L. K., Vendelbo, M. H. & Jørgensen, N. P. (2025). [¹⁸F]Fluorodeoxyglucose Positron Emission Tomography for diagnosis and monitoring of acute Staphylococcus aureus vascular graft infection in a rat model. The Journal of Infectious Diseases, Article jiaf594. Advance online publication. https://doi.org/10.1093/infdis/jiaf594

Godoy, L. D. & Wegener, G. (2025). Acta Neuropsychiatrica embraces full open access: towards a new era of global knowledge sharing. Acta Neuropsychiatrica, 37, e2. Article e2. https://doi.org/10.1017/neu.2024.66

H.Rafati, A., Rasmusson, S., Marziyeh Jabbari Shiadeh, S., Rosario, F. J., Jansson, T., Mallard, C. & Ardalan, M. (2025). A Novel Framework for Quantitative Analysis of Neuronal Primary Cilia in Brain Tissue.

Jabbari Shiadeh, S. M., Chan, W. K., Rasmusson, S., Hassan, N., Joca, S., Westberg, L., Elfvin, A., Mallard, C. & Ardalan, M. (2025). Bidirectional crosstalk between the gut microbiota and cellular compartments of brain: Implications for neurodevelopmental and neuropsychiatric disorders. Translational Psychiatry, 15(1), Article 278. https://doi.org/10.1038/s41398-025-03504-2

Jakobsen, E. M., Alam, M. Z. B. & Winterdahl, M. (2025). Exploring the link between the use of oral contraceptives and intrauterine devices, and alcohol consumption in young Danish women. Maturitas, 199, Article 108643. https://doi.org/10.1016/j.maturitas.2025.108643

Jensen, N. J., Porse, A. J., Wodschow, H. Z., Speyer, H., Krogh, J., Marner, L., Gejl, M., Gjedde, A. & Rungby, J. (2025). Relation of Insulin Resistance to Brain Glucose Metabolism in Fasting and Hyperinsulinemic States: A Systematic Review and Meta-analysis. Journal of Clinical Endocrinology and Metabolism, 110(2), e525-e537. https://doi.org/10.1210/clinem/dgae570

Jensen, A. A., Cecchi, C. R., Hibicke, M., Bach, A. H., Kaadt, E., Märcher-Rørsted, E., Nichols, C. D., Elfving, B. & Kristensen, J. L. (2025). The Selective Serotonin 5-HT_2A Receptor Agonist (S)-3-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)piperidine (LPH-5) Induces Persistent and Robust Antidepressant-Like Effects in Rodents. ACS Pharmacology and Translational Science, 8(6), 1791-1803. https://doi.org/10.1021/acsptsci.5c00208

Joca, S. (2025). Neurodegenerative disorders: Advances in neurobiology and new treatment perspectives. Basic and Clinical Pharmacology and Toxicology, 136(1), Article e14098. https://doi.org/10.1111/bcpt.14098

Johannessen, K., Braný, D., Dvorská, D., Krivošová, M., Oppa, M., Ondrejka, I., Strnádel, J., Ferencová, N., Tonhajzerová, I., Danková, Z., Halašová, E., Mokrý, J. & Elfving, B. (2025). Dysregulated miR-1246 and miR-1253 link inflammatory protein markers in plasma to major depressive disorder in female adolescents. Brain, Behavior, and Immunity - Health, 49, Article 101108. https://doi.org/10.1016/j.bbih.2025.101108

Kai, L. M., Parada Iglesias, L., Kõiv, K., Harro, J. & Wegener, G. (2025). Ultrasonic vocalisations in the Flinders Sensitive Line rat, a genetic animal model of depression. Acta Neuropsychiatrica, 37, Article e3. https://doi.org/10.1017/neu.2024.61

Karsberg, S. H., Thylstrup, B., Thomsen, K. R., Grassi-Oliveira, R., Pedersen, M. M. & Hesse, M. (2025). The Impact of Severe Trauma Exposure in Late Childhood on Longitudinal Treatment Outcomes in Adolescents and Young Adults in Treatment for Drug Use Disorders: A Record-Linkage Study. International Journal of Mental Health and Addiction, 23(2), 1518–1542. https://doi.org/10.1007/s11469-023-01182-z

Knudsen, C., Thomsen, M. B., Højgaard, K., Christiansen, S. L., Wiborg, O., Müller, H. K., Landau, A. M. & Elfving, B. (2025). Agomelatine normalizes region-specific, diurnal mGluR5 dysregulation in a chronic mild stress rat model of depression. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 143, Article 111572. https://doi.org/10.1016/j.pnpbp.2025.111572

Kølbæk, P., Jensen, B. D., Larsen, E. R. & Østergaard, S. D. (2025). Improving the Accuracy and Reliability of Ratings on the Hamilton Depression Rating Scale via a Video-Based Training Program. Acta Psychiatrica Scandinavica, 152(6), 462-472. https://doi.org/10.1111/acps.70029

Krieger, K., Pyka, T., Mingels, C., Sari, H., Gjedde, A., Rominger, A. & Cumming, P. (2025). Kinetics of the amino acid uptake tracer O-(2-[¹⁸F]fluoroethyl)-L-tyrosine (FET) in human brain. EJNMMI research, 15(1), Article 90. https://doi.org/10.1186/s13550-025-01279-7

Krogsbaek, M., Larsen, N. Y., Yarmahmoudi, F., Søndergaard, J., Landau, A. M., Sanchez, C. & Nyengaard, J. R. (2025). Chronic olanzapine treatment leads to increased opioid receptor expression and changes in feeding regulating neurons in the female rat hypothalamus. Psychoneuroendocrinology, 171, Article 107225. https://doi.org/10.1016/j.psyneuen.2024.107225

Landau, A. (2025). Novel Imaging Biomarkers for Brain PET Imaging. Biomolecules, 15(4), 517. Article 517. https://doi.org/10.3390/biom15040517

Malhi, G. S., Bell, E., Szymaniak, K., Looi, J. C. L., Fernandez-Egea, E. & Wegener, G. (2025). Subversion of publishing comes to a boil: is it time to lance it? British Journal of Psychiatry, 227(2), 517-518. https://doi.org/10.1192/bjp.2025.10332

Malhi, G. S., Marsh, J., Ongur, D., Cosci, F., Krystal, J. H., Cropsey, K. L., Wegener, G., Redline, S., Pariante, C. M., Hageman, I., Carter, C., Rief, W., Emsley, R., DeLisi, L. E., Cipriani, A., Crespo-Facorro, B., Kisely, S., Yatham, L. N., Looi, J. C. L. ... Dazzan, P. (2025). Truthful communication of mental science: pledge to our patients and profession. British Journal of Psychiatry, 226(5), 253-255. https://doi.org/10.1192/bjp.2025.94

Møller, J. E., Kai, L. M., Skipper, M., Hansen, M. B., Randsbæk, F., Matthiesen, S. S. & Malling, B. V. (2025). How Doctors Talk About Medical Errors: A Qualitative Study of Junior Doctors' Experiences. Qualitative Health Research, 35(10-11), 1118-1130. https://doi.org/10.1177/10497323241286037

Okeoma, C. M., Naushad, W., Okeoma, B. C., Gartner, C., Santos-Ortega, Y., Vary, C., Lima-Bastos, S., Carregari, V. C., Larsen, M. R., Noghero, A., Walss-Bass, C. & Grassi-Oliveira, R. (2025). Lipidomic and proteomic insights from extracellular vesicles in the postmortem dorsolateral prefrontal cortex reveal substance use disorder-induced brain changes. Translational Psychiatry, 15(1), Article 284. https://doi.org/10.1038/s41398-025-03512-2

Orso, R., Viola, T. W., Heberle, B. A., Creutzberg, K. C., Lumertz, F. S. & Grassi-Oliveira, R. (2025). Sex-Specific Effects of Early-Life Stress Exposure on Memory Performance and the Medial Prefrontal Cortex Transcriptomic Pattern in Adolescent Mice. Molecular Neurobiology, 62(7), 8728-8737. https://doi.org/10.1007/s12035-025-04803-x

Østergaard, H. D., Pallesen, K. J., Nielsen, M. N., Fjorback, L., Juul, L. & Winterdahl, M. (2025). Effects of mindfulness-based stress reduction on neuropeptide Y plasma levels in stressed individuals. Journal of Psychiatric Research, 181, 400-404. https://doi.org/10.1016/j.jpsychires.2024.12.011

Ota, V. K., Oliveira, A. M., Bugiga, A. V. G., Conceição, H. B., Galante, P. A. F., Asprino, P. F., Schäfer, J. L., Hoffmann, M. S., Bressan, R., Brietzke, E., Manfro, G. G., Grassi-Oliveira, R., Gadelha, A., Rohde, L. A., Miguel, E. C., Pan, P. M., Santoro, M. L., Salum, G. A., Carvalho, C. M. & Belangero, S. I. (2025). Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study. Frontiers in Psychiatry, 16, Article 1505421. https://doi.org/10.3389/fpsyt.2025.1505421

Overby, M., Desdorf, L. M., Kjølbye, L., Rosendahl, T., Weick, J. P., Schiøtt, B., Berglund, N. A. & Müller, H. K. (2025). Transmembrane domain interactions underlie NSG1 regulation of sortilin ectodomain shedding. Journal of Biological Chemistry, 301(11), Article 110804. https://doi.org/10.1016/j.jbc.2025.110804

Petersen, E. E. S., Kiy, F., Kesmodel, U. S., Pop, M. L., Kjaersdam Telléus, G., Stensballe, A., Dal, J., Højgaard, A. & Winterdahl, M. (2025). Gender-Affirming Hormone Therapy, Quality of Life, and the Role of Oestradiol and Testosterone in Transgender Individuals. Acta Neuropsychiatrica, 37, Article e68. https://doi.org/10.1017/neu.2025.10018

Rafati, A. H., Joca, S., Vontell, R. T., Mallard, C., Wegener, G. & Ardalan, M. (2025). A Model-Based Approach to Neuronal Electrical Activity and Spatial Organization Through the Neuronal Actin Cytoskeleton. Methods and Protocols, 8(4), Article 76. https://doi.org/10.3390/mps8040076

Ramos, J. K. N., Gravet, E. H., Junger-Santos, I., Ciochetti, N. P., Bandeira, C. E., de Araujo Tavares, M. E., de Oliveira, V. F., Vitola, E. S., Rohde, L. A., Grassi-Oliveira, R., da Silva, B. S., Bau, C. H. D. & Rovaris, D. L. (2025). Shared biological pathways linking ADHD and cortisol variability are related to externalizing behaviors. Psychoneuroendocrinology, 181, Article 107587. https://doi.org/10.1016/j.psyneuen.2025.107587

Saboori Amleshi, R., Ilaghi, M., Rezaei, M., Zangiabadian, M., Rezazadeh, H., Wegener, G. & Arjmand, S. (2025). Predictive utility of artificial intelligence on schizophrenia treatment outcomes: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews, 169, 105968. Article 105968. https://doi.org/10.1016/j.neubiorev.2024.105968

Salum, G. A., De Giusti, C., Souza, L., Juk, J., Costa, R., Sugaya, L., Caye, A., Simioni, A., Rocha, P. B., Manfro, G. G., Ito, L. T., Da Silva, F., Duarte, I., Esper, N., Anés, M., Damiano, R. F., Satterthwaite, T. D., Carvalho, C. M., Bado, P. ... Pan, P. M. (2025). Cohort Profile: Brazilian High-Risk Cohort for Mental Health Conditions (BHRC). International Journal of Epidemiology, 54(6), Article dyaf192. https://doi.org/10.1093/ije/dyaf192

Santi, M. M., Genovese, E., Schou, T. M., da Silva, M., Erhardt, S., Schwieler, L., Weidenfors, J. A., Marino, G., Paludan, S. R., Joca, S., Wegener, G., Reinert, L. & Bay-Richter, C. (2025). Neuropsychiatric- and cognitive post-acute sequelae of SARS-CoV-2 infection - evidence from K18-hACE C57BL/6 J mice. The international journal of neuropsychopharmacology, 28(10), Article pyaf072. https://doi.org/10.1093/ijnp/pyaf072

Schuurmans, I. K., Mulder, R. H., Baltramonaityte, V., Lahtinen, A., Qiuyu, F., Rothmann, L. M., Staginnus, M., Tuulari, J. J., Burt, S. A., Buss, C., Craig, J. M., Donald, K. A., Eriksson, J. G., Felix, J. F., Freeman, T. P., Grassi-Oliveira, R., Huels, A., Hyde, L. W., Jones, S. A. ... Cecil, C. A. M. (2025). Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium. Molecular Psychiatry. Advance online publication. https://doi.org/10.1038/s41380-025-03203-w

Silva, N. R., Arjmand, S., Domingos, L. B., Chaves-Filho, A. M., Mottin, M., Real, C. C., Waszkiewicz, A. L., Gobira, P. H., Ferraro, A. N., Landau, A. M., Andrade, C. H., Müller, H. K., Wegener, G. & Joca, S. R. L. (2025). Modulation of the endocannabinoid system by (S)-ketamine in an animal model of depression. Pharmacological Research, 211, 107545. Article 107545. https://doi.org/10.1016/j.phrs.2024.107545

Simonsen, B., Rübsam, H., Kolte, M. V., Larsen, M. M., Krönauer, C., Gysel, K., Laursen, M., Feng, F., Sezer, G., Oldroyd, G. E. D., Stougaard, J., Fort, S., Radutoiu, S. & Andersen, K. R. (2025). The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity. New Phytologist, 246(4), 1423-1431. https://doi.org/10.1111/nph.70067

Smedegaard, S., Kampmann, U., Ovesen, P. G., Suder, L. B., Knudsen, J. H., Wegener, G., Brunsgaard, L. H. & Rittig, N. (2025). Premeal Whey Protein Lowers Postprandial Blood Glucose in Women With Gestational Diabetes Mellitus: A Randomized, Crossover Clinical Trial. Diabetes Care, 48(6), 1022-1031. https://doi.org/10.2337/dc24-2831

Søkilde, R., Kaadt, E., Kristensen, L. S., Venø, M. T., Kjems, J., Nyengaard, J. R., Nielsen, B. S. & Elfving, B. (2025). Application of microRNA In Situ Hybridization on Long-term Stored Human Formalin-fixed Paraffin-embedded Brain Samples from Psychiatric Patients. Molecular Neurobiology, 62(10), 12736-12746. https://doi.org/10.1007/s12035-025-05077-z

Sun, L., Landau, A. M., Tang, J. & Roivainen, A. (2025). Dark seasons enhance brain and brown adipose tissue interactions related to mu-opioid receptor signaling. European journal of nuclear medicine and molecular imaging, 52(10), 3534-3539. https://doi.org/10.1007/s00259-025-07272-5

Turone, I., Petersen, E. E. S., Winterdahl, M., Serafini, G. & Pop, M. L. (2025). Gender Minority Stress and Resilience, Mental Health and Wellbeing in Transgender and Gender-Diverse Individuals: A Narrative Review. Current Sexual Health Reports, 17(1), Article 18. https://doi.org/10.1007/s11930-025-00414-8

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Revised 04.03.2025

Karen Jul Madsen