Witt, N. A., Lee, B., Ghent, K., Zhang, W. Q., Pehrson, A. L.
, Sánchez, C. & Gould, G. G. (2019).
Vortioxetine Reduces Marble Burying but Only Transiently Enhances Social Interaction Preference in Adult Male BTBR T+Itpr3tf/J Mice.
ACS Chemical Neuroscience,
10(10), 4319-4327.
https://doi.org/10.1021/acschemneuro.9b00386
Glud, A. N., Jakobsen, S., Landau, A., Alstrup, A. K. O. & Sorensen, J. C. (2019).
Visualization of intrathecal delivery by PET-imaging.
Journal of Neuroscience Methods,
317, 45-48.
https://doi.org/10.1016/j.jneumeth.2019.02.003
Gaspar, H. A., Gerring, Z., Hübel, C., Middeldorp, C. M., Derks, E. M., Breen, G. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019).
Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder.
Translational Psychiatry,
9(1), Article 117.
https://doi.org/10.1038/s41398-019-0451-4
Madsen, T.
, Buttenschøn, H. N., Uher, R., Behrendt-Møller, I., Perroud, N., Maier, W., Hauser, J., Dernovsek, M. Z., Henigsberg, N., Souery, D., Rietschel, M., McGuffin, P., Aitchison, K. J.
, Mors, O. & Köhler-Forsberg, O. (2019).
Trajectories of Suicidal Ideation During 12 Weeks of Escitalopram or Nortriptyline Antidepressant Treatment Among 811 Patients With Major Depressive Disorder.
Journal of Clinical Psychiatry,
80(4), Article 18m12575.
https://doi.org/10.4088/JCP.18m12575
Abildgaard, A., Kern, T. S., Pedersen, O., Hansen, T.
, Wegener, G. & Lund, S. (2019).
The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats.
European Neuropsychopharmacology,
29(1), 98-110.
https://doi.org/10.1016/j.euroneuro.2018.10.011
Tillmann, S., Skibdal, H. E., Christiansen, S. H., Gøtzsche, C. R., Hassan, M., Mathé, A. A.
, Wegener, G. & Woldbye, D. P. D. (2019).
Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats.
Behavioural Brain Research,
367, 28-34.
https://doi.org/10.1016/j.bbr.2019.03.039
Winterdahl, M., Noer, O., Orlowski, D., Schacht, A. C., Jakobsen, S., Alstrup, A. K. O., Gjedde, A. & Landau, A. (2019).
Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain.
Scientific Reports,
9(1), Article 16918.
https://doi.org/10.1038/s41598-019-53430-9
Treccani, G., Ardalan, M., Chen, F., Musazzi, L., Popoli, M.
, Wegener, G., Nyengaard, J. R. & Müller, H. K. (2019).
S-Ketamine Reverses Hippocampal Dendritic Spine Deficits in Flinders Sensitive Line Rats Within 1 h of Administration.
Molecular Neurobiology,
56(11), 7368-7379.
https://doi.org/10.1007/s12035-019-1613-3
Damsbo, A. G., Kraglund, K. L.
, Buttenschøn, H. N., Johnsen, S. P.
, Andersen, G. & Mortensen, J. K. (2019).
Serotonergic Regulation and Cognition after Stroke: The Role of Antidepressant Treatment and Genetic Variation.
Cerebrovascular Diseases,
47(1-2), 72-79.
https://doi.org/10.1159/000498911
Ribeiro, D. E., Casarotto, P. C., Staquini, L., Pinto E Silva, M. A., Biojone, C.
, Wegener, G. & Joca, S. (2019).
Reduced P2X receptor levels are associated with antidepressant effect in the learned helplessness model.
PeerJ,
7(10), Article e7834.
https://doi.org/10.7717/peerj.7834
Jefsen, O., Højgaard, K., Christiansen, S. L.
, Elfving, B., Nutt, D. J.
, Wegener, G. & Müller, H. K. (2019).
Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat.
Acta Neuropsychiatrica,
31(4), 213-219.
https://doi.org/10.1017/neu.2019.15
Corsi-Zuelli, F., Fachim, H., Loureiro, C., Shuhama, R., Bertozi, G.
, Joca, S., Menezes, P. R., Louzada-Junior, P. & Del-Ben, C. M. (2019).
Prolonged Periods of Social Isolation From Weaning Reduce the Anti-inflammatory Cytokine IL-10 in Blood and Brain.
Frontiers in Neuroscience,
12(JAN), Article 1011.
https://doi.org/10.3389/fnins.2018.01011
Ribeiro, D. E., Roncalho, A. L., Glaser, T., Ulrich, H.
, Wegener, G. & Joca, S. (2019).
P2X7 Receptor Signaling in Stress and Depression.
International Journal of Molecular Sciences ,
20(11), Article 2778.
https://doi.org/10.3390/ijms20112778
Mansouri, M., Pouretemad, H., Roghani, M.
, Wegener, G. & Ardalan, M. (2019).
Oxytocin improves autistic-like behaviors induced by maternal deprivation in female rats.
DANESHVAR MEDICINE,
27(144 #T00275), 49-60.
https://www.sid.ir/en/Journal/ViewPaper.aspx?ID=716476
Smith, K. L., Cunningham, J. I., Eyerman, D. J., Dean, R. L., Deaver, D. R.
& Sanchez, C. (2019).
Opioid system modulators buprenorphine and samidorphan alter behavior and extracellular neurotransmitter concentrations in the Wistar Kyoto rat.
Neuropharmacology,
146(March), 316-326.
https://doi.org/10.1016/j.neuropharm.2018.11.015
Joca, S., Sartim, A., Roncalho, A., Diniz, C.
& Wegener, G. (2019).
Nitric oxide signalling and antidepressant action revisited.
Cell and Tissue Research,
377(1), 45-58.
https://doi.org/10.1007/s00441-018-02987-4
Metaxas, A., Anzalone, M., Vaitheeswaran, R., Petersen, S.
, Landau, A. M. & Finsen, B. (2019).
Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer's disease.
Alzheimer's Research & Therapy,
11(1), Article 38.
https://doi.org/10.1186/s13195-019-0491-2
Khan, A. R.
, Hansen, B., Danladi, J., Chuhutin, A., Wiborg, O.
, Nyengaard, J. R. & Jespersen, S. (2019).
Neurite atrophy in dorsal hippocampus of rat indicates incomplete recovery of chronic mild stress induced depression: Neurite atrophy in the hippocampus show partial recovery of depression.
NMR in Biomedicine,
32(3).
https://doi.org/doi.org/10.1002/nbm.4057
Bannach-Brown, A., Przybyła, P., Thomas, J., Rice, A. S. C., Ananiadou, S., Liao, J. & Macleod, M. R. (2019).
Machine learning algorithms for systematic review: Reducing workload in a preclinical review of animal studies and reducing human screening error.
Systematic Reviews,
8(1), Article 23.
https://doi.org/10.1186/s13643-019-0942-7
Bay-Richter, C., Buttenschøn, H. N., Mors, O., Eskelund, A., Budac, D., Kærlev, L.
& Wegener, G. (2019).
Latent toxoplasmosis and psychiatric symptoms - A role of tryptophan metabolism? Journal of Psychiatric Research,
110, 45-50.
https://doi.org/10.1016/j.jpsychires.2018.12.016
Bay-Richter, C., Petersen, E., Liebenberg, N.
, Elfving, B. & Wegener, G. (2019).
Latent toxoplasmosis aggravates anxiety- and depressive-like behaviour and suggest a role of gene-environment interactions in the behavioural response to the parasite.
Behavioural Brain Research,
364(May), 133-139.
https://doi.org/10.1016/j.bbr.2019.02.018
Kohtala, S., Theilmann, W., Rosenholm, M.
, Müller, H. K., Kiuru, P.
, Wegener, G., Yli-Kauhaluoma, J. & Rantamäki, T. (2019).
Ketamine-induced regulation of TrkB-GSK3β signaling is accompanied by slow EEG oscillations and sedation but is independent of hydroxynorketamine metabolites.
Neuropharmacology,
157, 107684. Article 107684.
https://doi.org/10.1016/j.neuropharm.2019.107684
Speed, M. S., Jefsen, O. H., Børglum, A. D., Speed, D. & Østergaard, S. D. (2019).
Investigating the association between body fat and depression via Mendelian randomization.
Translational Psychiatry,
9(1), Article 184.
https://doi.org/10.1038/s41398-019-0516-4
Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O'Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C. ... Binder, E. B. (2019).
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.
Nature Communications,
10, Article 2548.
https://doi.org/10.1038/s41467-019-10461-0
Rydbirk, R.
, Elfving, B., Folke, J., Pakkenberg, B., Winge, K., Brudek, T. & Aznar, S. (2019).
Increased prefrontal cortex interleukin-2 protein levels and shift in the peripheral T cell population in progressive supranuclear palsy patients.
Scientific Reports,
9(1), Article 7781.
https://doi.org/10.1038/s41598-019-44234-y
Metaxas, A., Thygesen, C., Briting, S. R. R.
, Landau, A., Darvesh, S. & Finsen, B. (2019).
Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer’s Disease Patients.
Frontiers in Cellular Neuroscience,
13, Article 538.
https://doi.org/10.3389/fncel.2019.00538
Kirkedal, C.
, Elfving, B., Müller, H. K., Moreira, F. A., Bindila, L., Lutz, B.
, Wegener, G. & Liebenberg, N. (2019).
Hemisphere-dependent endocannabinoid system activity in prefrontal cortex and hippocampus of the Flinders Sensitive Line rodent model of depression.
Neurochemistry International,
125(May), 7-15.
https://doi.org/10.1016/j.neuint.2019.01.023
Winther, G., Eskelund, A., Richter, C. B., Elfving, B., Müller, H. K., Lund, S. & Wegener, G. (2019).
Grandmaternal High-fat Diet Primed Anxiety-like Behaviour in the Second-Generation Female Offspring.
Behavioural Brain Research,
359, 47-55.
https://doi.org/10.1016/j.bbr.2018.10.017
Howard, D. M., Adams, M. J., Clarke, T.-K., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J. ... 23andMe Research Team (2019).
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
Nature Neuroscience,
22(3), 343-352.
https://doi.org/10.1038/s41593-018-0326-7
Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M.
, Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L. ... Levinson, D. F. (2019).
Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts.
Biological Psychiatry,
85(12), 1065-1073.
https://doi.org/10.1016/j.biopsych.2019.02.022
Pereira, V. S.
, Joca, S. R. L., Harvey, B. H.
, Elfving, B. & Wegener, G. (2019).
Esketamine and Rapastinel, but not Imipramine, have antidepressant-like effect in a treatment-resistant animal model of depression.
Acta Neuropsychiatrica,
31(5), 258-265.
https://doi.org/10.1017/neu.2019.25
Mansouri, M., Pouretemad, H., Roghani, M.
, Wegener, G. & Ardalan, M. (2019).
Environmental Enrichment Ameliorates Repetitive Behaviors in a Rat Model of Autism.
Journal of Neurodevelopmental Cognition,
1, 108-117.
http://jncog.sbu.ac.ir/issue/view/1326
Silote, G. P., Sartim, A., Sales, A.
, Eskelund, A., Guimarães, F. S.
, Wegener, G. & Joca, S. (2019).
Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms.
Journal of Chemical Neuroanatomy,
98, 104-116.
https://doi.org/10.1016/j.jchemneu.2019.04.006
Landau, A., Alstrup, A. K. O., Noer, O., Winterdahl, M., Audrain, H., Møller, A., Videbech, P.
, Wegener, G., Gjedde, A. & Doudet, D. J. (2019).
Electroconvulsive stimulation differentially affects [11C]MDL100,907 binding to cortical and subcortical 5HT2A receptors in porcine brain.
Journal of Psychopharmacology,
33(6), 714-721. Article 269881119836212.
https://doi.org/10.1177/0269881119836212
Argyrousi, EK., Lagatta, DC., Schulutter, A., Weidner, MT., Zoller, J., van Goethem, NP.
, Joca, S., van den Hove, DLA. & Prickaerts, J. (2019).
Effects of DNA methyltransferase inhibition on pattern separation performance in mice. Neurobiology of Learning and Memory,
159, 6-15.
https://doi.org/10.1016/j.nlm.2019.02.003
Köhler-Forsberg, O., Larsen, E. R., Buttenschøn, H. N., Rietschel, M., Hauser, J., Souery, D., Maier, W., Farmer, A., McGuffin, P., Aitchison, K. J., Uher, R.
& Mors, O. (2019).
Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder.
British Journal of Psychiatry,
215(2), 494-501.
https://doi.org/10.1192/bjp.2018.302
Diniz, C., Biojone, C.
, Joca, S., Rantamaki, T., Castren, E., Guimaraes, F. & Casarotto, P. (2019).
Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors.
PeerJ,
7(2), Article e6493.
https://doi.org/10.7717/peerj.6493
Elfving, B., Müller, H. K., Oliveras, I., Østerbøg, T. B., Rio-Alamos, C., Sanchez-Gonzalez, A., Tobeña, A., Fernandez-Teruel, A. & Aznar, S. (2019).
Differential expression of synaptic markers regulated during neurodevelopment in a rat model of schizophrenia-like behavior.
Progress in Neuro-Psychopharmacology and Biological Psychiatry,
95, Article 109669.
https://doi.org/10.1016/j.pnpbp.2019.109669
Herzog, D.
, Wegener, G., Lieb, K., Müller, M.
& Treccani, G. (2019).
Decoding the Mechanism of Action of Rapid-Acting Antidepressant Treatment Strategies: Does Gender Matter? International Journal of Molecular Sciences (Online),
20(4), Article 949.
https://doi.org/10.3390/ijms20040949
Hvilsom, A. S. T.
, Lillethorup, T. P., Iversen, P., Doudet, D. J.
, Wegener, G. & Landau, A. M. (2019).
Cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli.
European Neuropsychopharmacology,
29(4), 493-500.
https://doi.org/10.1016/j.euroneuro.2019.02.009
Tornese, P., Sala, N., Bonini, D., Bonifacino, T., La Via, L., Milanese, M.
, Treccani, G., Seguini, M., Ieraci, A., Mingardi, J.
, Nyengaard, J. R., Calza, S., Bonanno, G.
, Wegener, G., Barbon, A., Popoli, M. & Musazzi, L. (2019).
Chronic mild stress induces anhedonic behavior and changes in glutamate release, BDNF trafficking and dendrite morphology only in stress vulnerable rats. The rapid restorative action of ketamine.
Neurobiology of Stress,
10, Article 100160.
https://doi.org/10.1016/j.ynstr.2019.100160