Ella Automated ELISA

Ella is a next-generation benchtop automated ELISA platform designed to deliver accurate, reproducible data with no manual steps. Utilizing a unique microfluidic design, the Ella platform’s Simple Plex assays are fully validated, highly sensitive and achieve fast, accurate multiplexing results in less than 90 minutes.

Why we use it

• In brain, CSF, serum, plasma, saliva, microdialysate, and cell supernatants we can measure biomarkers and inflammatory molecules in humans and experimental animals

• The assays are very sensitive with a dynamic range >4 logs and require as little as 2.5 uL of sample. Aditionally, a pre-calibrated standard curve is build in, leading to increased accuracy and reproducibility

• Compared to other multiplex ELISA systems, Ella is automated which eliminates pipetting errors. Furthermore, no multianalyte cross reactivity occurs, as all analytes are physically separated into different microfluidic channels.

Our Equipment

• Ella next-generation benchtop automated ELISA platform, which pneumatically interfaces with the Simple Plex assay cartridges, with pre-loaded reagents

• Each fluidic channel contains glass nanoreactors coated with capture antibodies, providing build-in replicate measurements for each analyte. A build-in fluorescent detection system is used

Applications in Neuropsychiatry

• Examination of inflammatory molecules in brain, CSF and blood from experimental models

• Longitudinal development of inflammatory markers in patient groups. Due to the high lot-to-lot consistency and user-to-user consistency sample inclusion can span long time periods