Oxford Nanopore Sequencing
Why we use it
• Full-length RNA sequencing to study isoforms and alternative splicing.
• Direct detection of DNA methylation (5mC, 5hmC and 6mA) without bisulfite conversion.
• Structural variant analysis in neurodevelopmental genes.
• Real-time sequencing, enabling rapid and adaptive data acquisition.
Our Equipment
• MinION – A portable, flexible device for targeted and real-time sequencing.
• P2 Solo – A high-throughput benchtop sequencer for larger-scale experiments.
.
.
Applications in Neurodevelopmental Research
• Epigenetic profiling of brain development and early-life stress.
• Alternative splicing analysis in neurodevelopmental disorders.
• Single-cell and multi-omics integration for neuronal differentiation studies.
• Mitochondrial DNA analysis in neural cells.
Nanopore sequencing enables high-resolution molecular insights into neurodevelopment and psychiatric disorders.