Rucker, J. J. H., Tansey, K. E., Rivera, M., Pinto, D., Cohen-Woods, S., Uher, R., Aitchison, K. J., Craddock, N., Owen, M. J., Jones, L., Jones, I., Korszun, A., Barnes, M. R., Preisig, M.
, Mors, O., Maier, W., Rice, J., Rietschel, M., Holsboer, F. ... Breen, G. (2016).
Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder.
Biological Psychiatry,
79(4), 329-336.
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Said, S., Malinauskaite, L., Grouleff, J., Shahsavar, A., Bjerregaard, H., Noer, P. R., Severinsen, K., Boesen, T., Schiøtt, B., Nissen, P. & Sinning, S. (2016).
The molecular mechanism for overcoming the ratelimiting step in monoamine neurotransmitter transport. Poster session presented at Årsmøde for Dansk Selskab for Farmakologi, Toksikologi og Medicinalkemi, Sandbjerg, Denmark.
Sinning, S., Said, S., Malinauskaite, L., Sahin, C., Grouleff, J., Shahsavar, A., Bjerregaard, H., Noer, P. R., Severinsen, K.
, Boesen, T., Schiøtt, B. & Nissen, P. (2016).
The molecular mechanism for overcoming the rate-limiting step in monoamine neurotransmitter transport. Poster session presented at Gordon Research Conferenc, Barga, Italy.
Sinning, S., Said, S., Malinauskaite, L., Sahin, C., Grouleff, J., Shahsavar, A., Bjerregaard, H., Noer, P. R., Severinsen, K.
, Boesen, T., Schiøtt, B. & Nissen, P. (2016).
The molecular mechanism for overcoming the rate-limiting step in monoamine neurotransmitter transport. Poster session presented at 9th SFB35 Symposium, Wien, Austria.
Starnawska, A., Demontis, D., Pen, A., Hedemand, A., Nielsen, A. L., Staunstrup, N. H., Grove, J., Als, T. D., Jarram, A., O'Brien, N. L.
, Mors, O., McQuillin, A.
, Børglum, A. D. & Nyegaard, M. (2016).
CACNA1C hypermethylation is associated with bipolar disorder.
Translational Psychiatry,
6(6), e831.
https://doi.org/10.1038/tp.2016.99
Starnawska, A., Demontis, D., McQuillin, A., O'Brien, N. L.
, Staunstrup, N. H., Mors, O., Nielsen, A. L., Børglum, A. D. & Nyegaard, M. (2016).
Hypomethylation of FAM63B in bipolar disorder patients.
Clinical Epigenetics (Print),
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Staunstrup, N. H., Starnawska, A., Nyegaard, M., Christiansen, L.
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Genome-wide DNA methylation profiling with MeDIP-seq using archived dried blood spots.
Clinical Epigenetics (Print),
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https://doi.org/10.1186/s13148-016-0242-1
Svenningsen, K., Venø, M. T., Henningsen, K., Mallien, A. S., Jensen, L.
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& Wiborg, O. (2016).
MicroRNA Profiling in the Medial and Lateral Habenula of Rats Exposed to the Learned Helplessness Paradigm: Candidate Biomarkers for Susceptibility and Resilience to Inescapable Shock.
PLOS ONE,
11(8), [e0160318].
https://doi.org/10.1371/journal.pone.0160318
Thomsen, M. B., Lillethorup, T. P., Jakobsen, S., Nielsen, E. H., Simonsen, M.
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Neonatal domoic acid alters in vivo binding of [(11)C]yohimbine to α2-adrenoceptors in adult rat brain.
Psychopharmacology,
233(21), 3779-3785.
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Treccani, G., Liebenberg, N., Tillmann, S., Musazzi, L., Milanese, M.
, Chen, F., Elfving, B., Wegener, G., Nyengaard, J. R., Popoli, M.
& Müller, H. K. (2016).
Functional and morphological changes induced by ketamine in the rat hippocampus. Poster session presented at 57th Annual Conference of the SCNP, Aarhus, Denmark.
Treccani, G., Liebenberg, N., Tillmann, S., Musazzi, L., Milanese, M.
, Chen, F., Elfving, B., Wegener, G., Nyengaard, J. R., Popoli, M.
& Müller, H. K. (2016).
Functional and morphological changes induced by ketamine in the rat hippocampus. Poster session presented at CINP Congress, Seoul.
Vandborg, S. K., Hartmann, T. B., Bennedsen, B. E., Pedersen, A. D. & Thomsen, P. H. (2016).
Can memory and executive functions in patients with obsessive-compulsive disorder predict outcome of cognitive behavioural therapy? Nordic Journal of Psychiatry,
70(3), 183-189.
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Viuff, A-C. F., Pedersen, L. H., Kyng, K., Staunstrup, N. H., Børglum, A. & Henriksen, T. B. (2016).
Antidepressant medication during pregnancy and epigenetic changes in umbilical cord blood: a systematic review.
Clinical Epigenetics (Print),
8(1).
https://doi.org/10.1186/s13148-016-0262-x
Viuff, A-C. F., Pedersen, L. H., Kyng, K. J., Staunstrup, N. H., Børglum, A. & Henriksen, T. B. (2016).
Epigenetic changes in newborns exposed to antidepressant medication during pregnancy - a planned genome wide study. Poster session presented at 2016 Epidemiology Conference of the Americas, Miami, United States.
Wei, Y. B., Liu, J. J., Villaescusa, J. C., Åberg, E., Brené, S.
, Wegener, G., Mathé, A. A. & Lavebratt, C. (2016).
Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression.
Translational Psychiatry,
6(8), e869.
https://doi.org/10.1038/tp.2016.136
Wei, Y. B., Melas, P. A., Villaescusa, J. C., Liu, J. J., Xu, N., Christiansen, S. H.
, Elbrønd-Bek, H., Woldbye, D. P. D.
, Wegener, G., Mathé, A. A. & Lavebratt, C. (2016).
MicroRNA 101b is downregulated in the prefrontal cortex of a genetic model of depression and targets the glutamate transporter SLC1A1 (EAAT3) in vitro.
International Journal of Neuropsychopharmacology,
19(12).
https://doi.org/10.1093/ijnp/pyw069
du Jardin, K. G., Müller, H. K., Sanchez, C., Wegener, G. & Elfving, B. (2016).
A single dose of vortioxetine, but not ketamine or fluoxetine, increases plasticity-related gene expression in the rat frontal cortex.
European Journal of Pharmacology,
786, 29-35.
https://doi.org/10.1016/j.ejphar.2016.05.029
du Jardin, K. G., Liebenberg, N., Müller, H. K., Elfving, B., Sanchez, C. & Wegener, G. (2016).
Differential interaction with the serotonin system by S-ketamine, vortioxetine, and fluoxetine in a genetic rat model of depression.
Psychopharmacology,
233(14), 2813-2825.
https://doi.org/10.1007/s00213-016-4327-5
du Jardin, K. G., Liebenberg, N., Müller, H. K., Elfving, B., Sánchez, C. & Wegener, G. (2016).
Endogenous 5-HT receptor stimulation is critical for the antidepressant-like effect of ketamine but not vortioxetine.
Acta Neuropsychiatrica,
28(S2), 19-20.
https://doi.org/10.1017/neu.2016.18
du Jardin, K. G., Müller, H. K., Elfving, B., Dale, E.
, Wegener, G. & Sanchez, C. (2016).
Potential involvement of serotonergic signaling in ketamine's antidepressant actions: A critical review.
Progress in Neuro-Psychopharmacology & Biological Psychiatry,
71, 27-38.
https://doi.org/10.1016/j.pnpbp.2016.05.007
Bak, S. T., Staunstrup, N. H., Starnawska, A., Daugaard, T. F., Nyegaard, M., Nyengaard, J. R., Børglum, A., Mors, O., Dorph-Petersen, K-A. & Nielsen, A. L. (2015).
Evaluating the Usability of Long-Term Stored Human Brain Bank Tissue for the Analysis of Epigenetic Markers. Poster session presented at Psykiatriens 10. forskningsdag, Risskov, Denmark.
Bay-Richter, C., Linderholm, K. R., Lim, CK., Samuelsson, M., Träskman-Bendz, L., Guillemin, G. J., Erhardt, S. & Brundin, L. (2015).
A role for inflammatory metabolites as modulators of the glutamate N-methyl-d-aspartate receptor in depression and suicidality.
Brain, Behavior, and Immunity,
43, 110-117.
https://doi.org/10.1016/j.bbi.2014.07.012
Bay-Richter, C., Janelidze, S., Sauro, A., Bucala, R., Lipton, J., Deierborg, T. & Brundin, L. (2015).
Behavioural and neurobiological consequences of macrophage migration inhibitory factor gene deletion in mice.
Journal of Neuroinflammation,
12, [163].
https://doi.org/10.1186/s12974-015-0387-4
Bjerregaard, H., Severinsen, K., Said, S., Wiborg, O. & Sinning, S. (2015).
A dualistic conformational response to substrate binding in the human serotonin transporter reveals a high affinity state for serotonin. Journal of Biological Chemistry,
290(12), 7747-55.
https://doi.org/10.1074/jbc.M114.573477
Bouzinova, E., Hangaard, L., Xie, Z.
, Staehr, C., Aalkjær, C. & Matchkov, V. (2015).
Pro-contractile action of the Na,K-ATPase/Src-kinase signaling pathway in the vascular wall.. Poster session presented at FEPS 2015, Kaunas, Lithuania.
https://doi.org/10.1111/apha.12626
Buttenschøn, H. N., Demontis, D., Ollendorff, M. K., Elfving, B., Jensen, S. M., Gustafsen, C., Kærlev, L.
, Petersen, C. M., Børglum, A., Mors, O. & Pedersen, S. G. (2015).
Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF.
Translational Psychiatry,
5(e677).
https://doi.org/10.1038/tp.2015.167
Buttenschøn, H. N., Demontis, D., Kaas, M.
, Elfving, B., mølgaard, S.
, Gustafsen, C., Kærlev, L.
, Petersen, C. M., Børglum, A., Mors, O.
& Pedersen, S. G. (2015).
Increased sortilin in depression.
Buttenschøn, H. N., Foldager, L., Elfving, B., Plougmann, P. H., Uher, R.
& Mors, O. (2015).
Neurotrophic factors in depression in response to treatment. Journal of Affective Disorders,
183, 287-94.
Børglum, A., Mors, O.
, Nyegaard, M., Christensen, J. H., Qvist, P., Rajkumar, A. P. & Wegener, G. (2015).
Heterozygous mouse with an inactivated brd1 allele and uses in psychiatry. (Patent No.
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https://patents.google.com/patent/US20150245597A1/
Chen, F., Rosenberg, R., Nyengaard, J. R. & Dorph-Petersen, K-A. (2015).
Hippocampus in depression, schizophrenia, and suicide: a postmortem stereological study of hippocampal volume and cell number. Abstract from 31st Nordic Congress of Psychiatry (NCP 2015), Copenhagen, Denmark.
Czéh, B., Varga, Z. K. K.
, Henningsen, K., Kovács, G. L., Miseta, A.
& Wiborg, O. (2015).
Chronic stress reduces the number of GABAergic interneurons in the adult rat hippocampus, dorsal-ventral and region-specific differences.
The Hippocampus,
25(3), 393-405.
https://doi.org/10.1002/hipo.22382
Dorph-Petersen, K-A., Rosenberg, R., Nyengaard, J. R. & Chen, F. (2015).
Hippocampus in schizophrenia, depression, and suicide: a postmortem stereological study of hippocampal volume and cell number.
Schizophrenia Bulletin,
41 (Suppl 1), S286.
https://doi.org/10.1093/schbul/sbv010
Du Jardin, K. G., Liebenberg, N., Müller, H. K., Elfving, B., Wegener, G. & Sanchez, C. (2015).
P. 2. e. 001 Differentiated antidepressant-like profiles of ketamine, fluoxetine and vortioxetine in Flinders Sensitive Line (FSL) rats depleted of endogenous 5-HT.
European Neuropsychopharmacology,
25, S431-S431.
Dudele, A., Fischer, C. W., Elfving, B., Wegener, G., Wang, T. & Lund, S. (2015).
Chronic exposure to low doses of lipopolysaccharide and high-fat feeding increases body mass without affecting glucose tolerance in female rats.
Physiological Reports,
3(11).
https://doi.org/10.14814/phy2.12584