Publications from TNU

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Sales, A. J., Hiroaki-Sato, V. A. & Joca, S. R. L. (2017). Participation of hippocampal nitric oxide synthase and soluble guanylate cyclase in the modulation of behavioral responses elicited by the rat forced swimming test. Behavioural Pharmacology, 28(1), 19-29. https://doi.org/10.1097/FBP.0000000000000263

Silva Pereira, V., Elfving, B., Joca, S. R. L. & Wegener, G. (2017). Ketamine and aminoguanidine differentially affect Bdnf and Mtor gene expression in the prefrontal cortex of adult male rats. European Journal of Pharmacology, 815, 304-311. https://doi.org/10.1016/j.ejphar.2017.09.029

Sinning, S. & Lund, A. E. (2017). Jungle Brew and Depression:Molecular Pharmacology of Ayahuasca Alkaloids on Monoamine Transporter Systems. Poster session presented at 9th Annual Meeting of the Danish Society of Pharmacology, Odense, Denmark.

Staunstrup, N. H., Starnawska, A., Nyegaard, M., Nielsen, A. L., Borglum, A. D. & Mors, O. (2017). The Genome-Wide DNA Methylation Profile of Peripheral Blood Is Not Systematically Changed by Short-Time Storage at Room Temperature. Epigenomes, 1(3), Article 23. https://doi.org/10.3390/epigenomes1030023

Stein, D. J. & Wegener, G. (2017). Discovery versus implementation research on mental disorders in low- and middle-income countries. Acta Neuropsychiatrica, 29(4), 191-192. https://doi.org/10.1017/neu.2017.25

Tillmann, S., Pereira, V. S., Liebenberg, N., Christensen, A. K. & Wegener, G. (2017). ZL006, a small molecule inhibitor of PSD-95/nNOS interaction, does not induce antidepressant-like effects in two genetically predisposed rat models of depression and control animals. P L o S One, 12(8), 1-17. Article e0182698. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182698

Topiol, S., Bang-Andersen, B., Sanchez, C., Plenge, P., Loland, C. J., Juhl, K., Larsen, K., Bregnedal, P. & Bogeso, K. P. (2017). X-ray structure based evaluation of analogs of citalopram: Compounds with increased affinity and selectivity compared with R-citalopram for the allosteric site (S2) on hSERT. Bioorganic & Medicinal Chemistry Letters, 27(3), 470-478. https://doi.org/10.1016/j.bmcl.2016.12.037

Treccani, G., Ardalan, M., Chen, F., Musazzi, Bettega, Mikkelsen, Popoli, M., Wegener, G., Nyengaard, J. R. & Müller, H. K. (2017). Behavioural and hippocampal morphological changes induced by short ketamine treatment in a genetic rat model displaying depressive-like behaviour. Abstract from European Neuropsychopharmacology.

Varga, Z., Csabai, D., Miseta, A., Wiborg, O. & Czeh, B. (2017). Chronic stress affects the number of GABAergic neurons in the orbitofrontal cortex of rats. Behavioural Brain Research, 316, 104-114. https://doi.org/10.1016/j.bbr.2016.08.030

Ventorp, F., Bay-Richter, C., Nagendra, A., Janelidze, S., Matsson, V., Lipton, J., Nordström, U., Westrin, Å., Brundin, P. & Brundin, L. (2017). Exendin-4 Treatment Improves LPS-Induced Depressive-Like Behavior Without Affecting Pro-Inflammatory Cytokines. Journal of Parkinson's Disease, 7(2), 263-273. https://doi.org/10.3233/JPD-171068

Waller, J. A., Nygaard, S. H., Li, Y., du Jardin, K. G., Tamm, J. A., Abdourahman, A., Elfving, B., Pehrson, A. L., Sánchez, C. & Wernersson, R. (2017). Neuroplasticity pathways and protein-interaction networks are modulated by vortioxetine in rodents. B M C Neuroscience, 18(1), 56. Article 56. https://doi.org/10.1186/s12868-017-0376-x

Wegener, G. (2017). Acta Neuropsychiatrica and social media. Acta Neuropsychiatrica, 29(6), 323. https://doi.org/10.1017/neu.2017.30

Winterdahl, M., Noer, O., Orlowski, D., Jakobsen, S., Alstrup, A. K. O., Scheel-Krüger, J., Kringelbach, M. L., Møller, A. & Landau, A. M. (2017). The “addicted” minipig brain: Sugar intake decreases dopamine D2/3 receptor availability in brain regions implicated in addiction. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.

Aagaard, J., Buus, N., Wernlund, A. G., Foldager, L. & Merinder, L. (2016). Clinically useful predictors for premature mortality among psychiatric patients visiting a psychiatric emergency room. International Journal of Social Psychiatry, 62(5), 462-470. https://doi.org/10.1177/0020764016642490

Abildgaard, A. (2016). Preclinical Studies on Metabolic Stress and Probiotic Treatment in Major Depressive Disorder. Health, Aarhus University.

Aldib, I., Gelbcke, M., Soubhye, J., Prévost, M., Furtmüller, P. G., Obinger, C., Elfving, B., Alard, I. C., Roos, G., Delporte, C., Berger, G., Dufour, D., Zouaoui Boudjeltia, K., Nève, J., Dufrasne, F. & Van Antwerpen, P. (2016). Novel bis-arylalkylamines as myeloperoxidase inhibitors: Design, synthesis, and structure-activity relationship study. European Journal of Medicinal Chemistry, 123, 746-62. https://doi.org/10.1016/j.ejmech.2016.07.053

Ardalan, M., Wegener, G., Polsinelli , B., Madsen, T. M. & Nyengaard, J. R. (2016). Neurovascular plasticity of the hippocampus one week after a single dose of ketamine in genetic rat model of depression. The Hippocampus, 26(11), 1414-1423. https://doi.org/10.1002/hipo.22617

Ardalan, M., Elfving, B., Jens, Mathe & Wegener, G. (2016). Sex-difference in rapid changes of hippocampal astrocytes and serum level of BDNF one hour after ketamine treatment. Abstract from European Neuropsychopharmacology.

Ardalan, M. (2016). The Influence of Rapid-acting Antidepressants on the Neuronal and Non-neuronal Plasticity of the Hippocampus in a Genetic Rat Model of Depression. Aarhus University.

Bannach-Brown, A., Liao, J., Wegener, G. & Macleod, M. (2016). Understanding in vivo modelling of depression in non-human animals: a systematic review protocol. Evidence-based Preclinical Medicine, 3(2), 20-27. https://doi.org/10.1002/ebm2.24

Brinkø, A., Larsen, M. T., Koldsø, H., Besenbacher, L. M., Kolind, A., Schiøtt, B., Sinning, S. & Jensen, H. H. (2016). Synthesis and inhibitory evaluation of 3-linked imipramines for the exploration of the S2 site of the human serotonin transporter. Bioorganic & Medicinal Chemistry, 24(12), 2725-2738. https://doi.org/10.1016/j.bmc.2016.04.039

Castagnini, A., Foldager, L., Caffo, E. & Thomsen, P. H. (2016). Early-adult outcome of child and adolescent mental disorders as evidenced by a national-based case register survey. European Psychiatry, 38, 45-50. https://doi.org/10.1016/j.eurpsy.2016.04.005

Chen, F., Rosenberg, R., Nyengaard, J. R. & Dorph-Petersen, K.-A. (2016). Stereological analysis of volume and cell number in the postmortem hippocampus in depression, schizophrenia, and suicide. Abstract from 57th Annual Meeting of the Scandinavian College of Neuropsychopharmacology, Aarhus, Denmark.

Chen, F., Rosenberg, R., Nyengaard, J. R. & Dorph-Petersen, K.-A. (2016). Stereological analysis of volume and cell number in the postmortem hippocampus in depression, schizophrenia, and suicide. Poster session presented at Neuroscience Day 2016, Aarhus, Denmark.

Chen, F., du Jardin, K. G., Waller, J. A., Sanchez, C., Nyengaard, J. R. & Wegener, G. (2016). Vortioxetine promotes early changes in dendritic morphology compared to fluoxetine in rat hippocampus. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 26(2), 234-245. https://doi.org/10.1016/j.euroneuro.2015.12.018

Christiansen, S., Bouzinova, E., Fahrenkrug, J. & Wiborg, O. (2016). Altered expression pattern of clock genes in a rat model of depression. International Journal of Neuropsychopharmacology, 19(11), 1-13. Article pyw061. https://doi.org/10.1093/ijnp/pyw061

Christiansen, S. L. (2016). Chronobiology in the Chronic Mild Stress Animal Model of Depression. Health, Aarhus University.

Christiansen, S. (2016). Disturbed diurnal rhythm of three classical phase markers in the chronic mild stress rat model of depression. 43-48. Poster session presented at Neuroscience day 2016.

Christiansen, S. L., Højgaard, K., Wiborg, O. & Bouzinova, E. (2016). Disturbed diurnal rhythm of three classical phase markers in the chronic mild stress rat model of depression. Journal of Neuroscience Research, 110, 43-48. https://doi.org/10.1016/j.neures.2016.03.002

Christiansen, S. (2016). The clockwork behind depression. Abstract from FENS 2016, København, Denmark.

Christiansen, S. L. (2016). The clockwork behind depression - disturbances of the diurnal rhythm in a rat model of depression. Abstract from Psykiatriens forskningsdag 2016, Risskov, Risskov, Denmark.

Dorph-Petersen, K.-A., Ziegel, J., Baddeley, A. & Jensen, E. B. V. (2016). Prediction of the variance of stereological volume estimates in systematic sampling with errors in sampling locations. Abstract from AU Workshop on Stochastic Geometry, Stereology and their Applications, Sønderborg, Denmark.

du Jardin, K. G., Müller, H. K., Sanchez, C., Wegener, G. & Elfving, B. (2016). A single dose of vortioxetine, but not ketamine or fluoxetine, increases plasticity-related gene expression in the rat frontal cortex. European Journal of Pharmacology, 786, 29-35. https://doi.org/10.1016/j.ejphar.2016.05.029

du Jardin, K. G., Liebenberg, N., Müller, H. K., Elfving, B., Sanchez, C. & Wegener, G. (2016). Differential interaction with the serotonin system by S-ketamine, vortioxetine, and fluoxetine in a genetic rat model of depression. Psychopharmacology, 233(14), 2813-2825. https://doi.org/10.1007/s00213-016-4327-5

du Jardin, K. G., Liebenberg, N., Müller, H. K., Elfving, B., Sánchez, C. & Wegener, G. (2016). Endogenous 5-HT receptor stimulation is critical for the antidepressant-like effect of ketamine but not vortioxetine. Acta Neuropsychiatrica, 28(S2), 19-20. https://doi.org/10.1017/neu.2016.18

du Jardin, K. G., Müller, H. K., Elfving, B., Dale, E., Wegener, G. & Sanchez, C. (2016). Potential involvement of serotonergic signaling in ketamine's antidepressant actions: A critical review. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 71, 27-38. https://doi.org/10.1016/j.pnpbp.2016.05.007

du Jardin, K. G. (2016). Unlocking the Antidepressant Potential of the Serotonergic-Glutamatergic Crosstalk. Faculty of Health Sciences, Aarhus University.

Eskelund, A., Budac, D. P., Sanchez, C., Elfving, B. & Wegener, G. (2016). Female Flinders Sensitive Line rats show estrous cycle-independent depression-like behavior and altered tryptophan metabolism. Neuroscience, 329, 337-348. https://doi.org/10.1016/j.neuroscience.2016.05.024

Gregersen, N., Buttenschøn, H. N., Hedemand, A., Nielsen, M. N., Dahl, H., Kristensen, A. S., Johansen, O., Woldbye, D., Erhardt, A., Kruse, T. A., Wang, A. G., Børglum, A. & Mors, O. (2016). Association between genes on chromosome 19p13.2 and panic disorder. Psychiatric Genetics, 26(6), 287-292. https://doi.org/10.1097/YPG.0000000000000147

Gregersen, N., Lescai, F., Liang, J., Li, Q., Als, T. D., Buttenschøn, H. N., Hedemand, A., Biskopstø, M., Wang, J., Wang, A., Børglum, A., Mors, O. & Demontis, D. (2016). Whole-exome sequencing implicates DGKH as a risk gene for panic disorder in the Faroese population. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 171(8), 1013-1022. https://doi.org/10.1002/ajmg.b.32464

Hansen, A. K., Knudsen, K., Lillethorup, T. P., Landau, A. M., Parbo, P., Fedorova, T., Audrain, H., Bender, D., Østergaard, K., Brooks, D. J. & Borghammer, P. (2016). In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET. Brain, 139(7), 2039-2049. https://doi.org/10.1093/brain/aww098

Happ, D. F. & Tasker, A. (2016). A method for objectively quantifying propidium iodide exclusion in organotypic hippocampal slice cultures. Journal of Neuroscience Methods, 269, 1-5. https://doi.org/10.1016/j.jneumeth.2016.05.006

Hjorth, P., Davidsen, A. S., Kilian, R., Jensen, S. O. W. & Munk-Jørgensen, P. (2016). Intervention to promote physical health in staff within mental health facilities and the impact on patients' physical health. Nordic Journal of Psychiatry, 70(1), 62-71. https://doi.org/10.3109/08039488.2015.1050452

Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W., Mattheisen, M., Morris, D., Mowry, B., Müller-Mhysok, B. ... Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016). No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study. P L o S Genetics, 12(10), e1006343. Article e1006343. https://doi.org/10.1371/journal.pgen.1006343

Khan, A. R., Chuhutin, A., Wiborg, O., Kroenke, C. D., Nyengaard, J. R., Hansen, B. & Jespersen, S. N. (2016). Biophysical modeling of high field diffusion MRI demonstrates micro-structural aberration in chronic mild stress rat brain. NeuroImage, 142, 421-430. https://doi.org/10.1016/j.neuroimage.2016.07.001

Khan, A. R., Chuhutin, A., Wiborg, O., Kroenke, C., Nyengaard, J. R., Hansen, B. & Jespersen, S. N. (2016). Chronic Mild Stress Induces Changes in Neurite Density in the Amygdala as Revealed by Diffusion MRI and Validated with Novel Histological Analyses. Abstract from ISMRM 2016 Annual Meeting & Exhibition, Singapore, Singapore.

Khan, A. R., Chuhutin, A., Wiborg, O., Kroenke, C. D., Nyengaard, J. R., Hansen, B. & Jespersen, S. N. (2016). Summary of high field diffusion MRI and microscopy data demonstrate microstructural aberration in chronic mild stress rat brain. Data in Brief, 8, 934-937. https://doi.org/10.1016/j.dib.2016.06.061

Kläning, U., Trumbetta, S. L., Gottesman, I. I., Skytthe, A., Kyvik, K. O. & Bertelsen, A. (2016). A Danish Twin Study of Schizophrenia Liability: Investigation from Interviewed Twins for Genetic Links to Affective Psychoses and for Cross-Cohort Comparisons. Behavior Genetics, 46(2), 193-204. https://doi.org/10.1007/s10519-015-9765-z

Kravtsova, V., Petrov, A. M., Matchkov, V., Bouzinova, E., Vasiliev, A. N., Benziane, B., Zefirov, A. L., Chibalin, A. V., Heiny, J. A. & Krivoi, II. (2016). Distinct alpha2 Na,K-ATPase membrane pools are differently involved in early skeletal muscle remodeling during disuse. Journal of General Physiology, 147(2), 175-188. https://doi.org/10.1085/jgp.201511494

Lund, A. E. & Sinning, S. (2016). Jungle brew: Molecular pharmacology of harmala alkaloids on monoamine transporters. Poster session presented at Årsmøde for Dansk Selskab for Farmakologi, Toksikologi og Medicinalkemi, Sandbjerg, Denmark.

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Revised 06.02.2023

Karen Jul Madsen