Publications from TNU
Anzabi, M., Ardalan, M., Iversen, N. K., H. Rafati, A., Hansen, B. & Østergaard, L. (2018). Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4. Frontiers in Cellular Neuroscience, 12(19), Article 19. https://doi.org/10.3389/fncel.2018.00019
Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2018). Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. PLoS One, 13(12), Article e0209160. https://doi.org/10.1371/journal.pone.0209160
Bak, S. T., Staunstrup, N. H., Starnawska, A., Daugaard, T. F., Nyengaard, J. R., Nyegaard, M., Børglum, A., Mors, O., Dorph-Petersen, K.-A. & Nielsen, A. L. (2018). Evaluating the Feasibility of DNA Methylation Analyses Using Long-Term Archived Brain Formalin-Fixed Paraffin-Embedded Samples. Molecular Neurobiology, 55(1), 668-681. https://doi.org/10.1007/s12035-016-0345-x
Bannach-Brown, A., Przybyła, P., Thomas, J., Rice, A. S. C., Ananiadou, S., Liao, J. & Macleod, M. R. (2018). Machine learning algorithms for systematic reviews: reducing workload in a preclinical review of animal studies and reducing human screening error. bioRxiv. http://biorxiv.org/content/early/2018/10/30/255760.abstract
Bay, V., Kjølby, B. F., Iversen, N. K., Mikkelsen, I. K., Ardalan, M., Nyengaard, J. R., Jespersen, S. N., Drasbek, K. R., Østergaard, L. & Hansen, B. (2018). Stroke infarct volume estimation in fixed tissue: Comparison of diffusion kurtosis imaging to diffusion weighted imaging and histology in a rodent MCAO model. PLoS One, 13(4), e0196161. Article e0196161. https://doi.org/10.1371/journal.pone.0196161
Bertelsen, F., Landau, A. M., Vase, K. H., Jacobsen, J., Scheel-Krüger, J. & Møller, A. (2018). Acute in vivo effect of valproic acid on the GABAergic system in rat brain: A [C-11]Ro15-4513 microPET study. Brain Research, 1680, 110-114. https://doi.org/10.1016/j.brainres.2017.12.018
Brown, E., Mc Veigh, C. J., Santos, L., Gogarty, M., Müller, H. K., Elfving, B., Brayden, D. J. & Haase, J. (2018). TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis. Neuropharmacology, 137, 211-220. https://doi.org/10.1016/j.neuropharm.2018.04.023
Buttenschøn, H. N., Elfving, B., Nielsen, M., Skeldal, S., Kaas, M., Mors, O. & Glerup, S. (2018). Exploring the sortilin related receptor, SorLA, in depression. Journal of Affective Disorders, 232, 260-267. https://doi.org/10.1016/j.jad.2018.02.050
Buttenschøn, H. N., Nielsen, M., Glerup, S. & Mors, O. (2018). Investigation of serum levels of sortilin in response to antidepressant treatment. Acta Neuropsychiatrica, 30(2), 111-116. https://doi.org/10.1017/neu.2017.13
Chen, F., Danladi, J., Ardalan, M., Elfving, B., Müller, H. K., Wegener, G., Sanchez, C. & Nyengaard, J. R. (2018). A critical role of mitochondria in BDNF-associated synaptic plasticity after one-week vortioxetine treatment. International Journal of Neuropsychopharmacology, 21(6), 603-615. https://doi.org/10.1093/ijnp/pyy022
Chen, F., Ardalan, M., Elfving, B., Wegener, G., M Madsen, T. & Nyengaard, J. R. (2018). Mitochondria are critical for BDNF-mediated Synaptic and Vascular plasticity of Hippocampus following Repeated Electroconvulsive Seizures. International Journal of Neuropsychopharmacology, 21(3), 291-304. https://doi.org/10.1093/ijnp/pyx115
Christensen, K. & Bertelsen, A. (2018). Irving I. Gottesman's Collaboration in Psychiatric Genetics Research in Denmark. Twin Research and Human Genetics, 21(4), 322-323. https://doi.org/10.1017/thg.2018.32
Czeh, B., Vardya, I., Varga, Z., Febbraro, F., Csabai, D., Martis, L.-S., Højgaard, K., Henningsen, K., Bouzinova, E., Miseta, A., Jensen, K. & Wiborg, O. (2018). Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats. Frontiers in Cellular Neuroscience, 12, Article 148. https://doi.org/10.3389/fncel.2018.00148
Dale, E., Grunnet, M., Pehrson, A. L., Frederiksen, K., Larsen, P. H., Nielsen, J., Stensbøl, T. B., Ebert, B., Yin, H., Lu, D., Liu, H., Jensen, T. N., Yang, C. R. & Sanchez, C. (2018). The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT
3
receptor expressing interneurons: An in vitro study in rat hippocampus slices. Brain Research, 1689, 1-11. https://doi.org/10.1016/j.brainres.2017.12.025
Dalsgaard, T., Kaadt, C. R. C., Askou, A. L., Bak, R. O., Andersen, P. O., Hougaard, D., Jensen, T. G., Dagnæs-Hansen, F., Mikkelsen, J. G., Corydon, T. J. & Aagaard, L. (2018). Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein. Molecular Therapy - Nucleic Acids, 12, 672-683. https://doi.org/10.1016/j.omtn.2018.07.005
de Jong, S., Diniz, M. J. A., Saloma, A., Gadelha, A., Santoro, M. L., Ota, V. K., Noto, C., Curtis, C., Newhouse, S. J., Patel, H., Hall, L. S., O Reilly, P. F., Belangero, S. I., Bressan, R. A., Breen, G. & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (Per Qvist and Preben Bo Mortensen, members of-) (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1(1), Article 163. https://doi.org/10.1038/s42003-018-0155-y
de Souza, M. M., Silote, G. P., Herbst, L. S., Funck, V. R., Joca, S. R. L. & Beijamini, V. (2018). The antidepressant-like effect of galanin in the dorsal raphe nucleus of rats involves GAL receptors. Neuroscience Letters, 681, 26-30. https://doi.org/10.1016/j.neulet.2018.05.029
Déziel, R. A. & Tasker, R. A. (2018). Bilateral ischaemic lesions of the medial prefrontal cortex are anxiogenic in the rat. Acta Neuropsychiatrica, 30(3), 181-186. https://doi.org/10.1017/neu.2017.32
Diniz, C. R. A. F., Casarotto, P., Fred, S. M., Biojone, C., Castren, E. & Joca, S. (2018). Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN. Neuropharmacology.
Diniz, C. R. A. F., Casarotto, P. C., Resstel, L. & Joca, S. R. L. (2018). Beyond good and evil: A putative continuum-sorting hypothesis for the functional role of proBDNF/BDNF-propeptide/mBDNF in antidepressant treatment. Neuroscience & Biobehavioral Reviews, 90, 70-83. https://doi.org/10.1016/j.neubiorev.2018.04.001
Diniz, C. R. A. F., Becari, C., Lesnikova, A., Biojone, C., Salgado, M. C. O., Salgado, H. C., Resstel, L. B. M., Guimaraes, F. S., Castren, E., Casarotto, P. & Joca, S. (2018). Elastase-2 Knockout Mice Display Anxiogenic- and Antidepressant-Like Phenotype: Putative Role for BDNF Metabolism in Prefrontal Cortex. Molecular Neurobiology.
du Jardin, K. G., Liebenberg, N., Cajina, M., Müller, H. K., Elfving, B., Sanchez, C. & Wegener, G. (2018). S-Ketamine Mediates Its Acute and Sustained Antidepressant-Like Activity through a 5-HT1B Receptor Dependent Mechanism in a Genetic Rat Model of Depression. Frontiers in Pharmacology, 8(JAN), 978. Article 978. https://doi.org/10.3389/fphar.2017.00978
Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S.-H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M. ... Lewis, C. M. (2018). Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 28(8), 945-954. https://doi.org/10.1016/j.euroneuro.2018.05.009
Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M. ... Lewis, C. M. (2018). New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation. The Pharmacogenomics Journal, 18(3), 413-421. https://doi.org/10.1038/tpj.2017.44
Felice, D., Guilloux, J. P., Pehrson, A., Li, Y., Mendez-David, I., Gardier, A. M., Sanchez, C. & David, D. J. (2018). Vortioxetine improves context discrimination in mice through a neurogenesis independent mechanism. Frontiers in Pharmacology, 9(MAR), Article 204. https://doi.org/10.3389/fphar.2018.00204
Futtrup, J., Nordentoft, M., Elfving, B. & Krogh, J. (2018). The association between norepinephrine and metabolism in patients with major depression. Neurology, Psychiatry and Brain Research, 30, 91-97. https://doi.org/10.1016/j.npbr.2018.07.002
Happ, D. F. & Tasker, R. A. (2018). Effects of α7 Nicotinic Receptor Activation on Cell Survival in Rat Organotypic Hippocampal Slice Cultures. Neurotoxicity Research, 33(4), 887-895. https://doi.org/10.1007/s12640-017-9854-2
Hillhouse, T. M., Merritt, C. R., Smith, D. A., Cajina, M., Sanchez, C., Porter, J. H. & Pehrson, A. L. (2018). Vortioxetine differentially modulates MK-801-induced changes in visual signal detection task performance and locomotor activity. Frontiers in Pharmacology, 9(SEP), Article 1024. https://doi.org/10.3389/fphar.2018.01024
Kaadt, E., Mumm, B. H., Andersen, S. N., Damgaard, C. K. & Elfving, B. (2018). Biomarkers of depression in skin - a novel approach. 1:1-23 (page 15). Abstract from SCNP - 2018, Aarhus.
Knudsen, J. K., Bundgaard-Nielsen, C., Hagstrøm, S., Sørensen, S. & Leutscher, P. (2018). geneksDen humane tarmmikrobiota. Ugeskrift for Læger, 180(6), 509-513.
Knudsen, J. K., Jensen, Z. F., Christensen, A. H., Günther, S., Nielsen, L. N., Leutscher, P. & Arnfred, S. (2018). Tarmmikrobiota og depression. Ugeskrift for Læger, 180(6), 514-517.
Landau, A. M., Alstrup, A. K. O., Audrain, H., Jakobsen, S., Simonsen, M., Møller, A., Videbech, P. B., Wegener, G., Gjedde, A. & Doudet, D. J. (2018). Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy. Journal of Cerebral Blood Flow and Metabolism, 38(5), 881-887. https://doi.org/10.1177/0271678X17705260
Laursen, L., Kristensen, K. B., Periole, X., Overby, M., Müller, H. K., Schiøtt, B. & Sinning, S. (2018). Cholesterol binding to a conserved site modulates conformation, pharmacology and transport kinetics of the human serotonin transporter. Journal of Biological Chemistry, 293(10), 3510-3523. https://doi.org/10.1074/jbc.M117.809046
Liebenberg, N., Jensen, E., Larsen, E. R., Kousholt, B. S., Pereira, V. S., Fischer, C. W. & Wegener, G. (2018). A Preclinical Study of Casein Glycomacropeptide as a Dietary Intervention for Acute Mania. International Journal of Neuropsychopharmacology, 21(5), 473-484. https://doi.org/10.1093/ijnp/pyy012
Lillethorup, T. P., Glud, A. N., Landeck, N., Alstrup, A. K. O., Jakobsen, S., Vang, K., Doudet, D. J., Brooks, D. J., Kirik, D., Hinz, R., Sorensen, J. C. & Landau, A. M. (2018). In vivo quantification of glial activation in minipigs overexpressing human alpha-synuclein. Synapse, 72(12), Article 22060. https://doi.org/10.1002/syn.22060
Lillethorup, T. P., GLUD, AN., Alstrup, A. K. O., Noer, O., Nielsen, E. H. T., Schacht, A. C., Landeck, N., Kirik, D., Orlowski, D., Sørensen, J. C. H., Doudet, D. J. & Landau, A. (2018). Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs. Scientific Reports, 8(1), Article 15715. https://doi.org/10.1038/s41598-018-34084-5
Lillethorup, T. P., Glud, A. N., Alstrup, A. K. O., Mikkelsen, T. W., Nielsen, E. H. T., Zaer, H., Doudet, D. J., Brooks, D. J., Sørensen, J. C. H., Orlowski, D. & Landau, A. M. (2018). Nigrostriatal proteasome inhibition impairs dopamine neurotransmission and motor function in minipigs. Experimental Neurology, 303, 142-152. https://doi.org/10.1016/j.expneurol.2018.02.005
Lisboa, S. F., Issy, A. C., Biojone, C., Montezuma, K., Fattori, V., Del-Bel, E. A., Guimarães, F. S., Cunha, F. Q., Verri, W. A. & Joca, S. R. L. (2018). Mice lacking interleukin-18 gene display behavioral changes in animal models of psychiatric disorders: Possible involvement of immunological mechanisms. Journal of Neuroimmunology, 314, 58-66. https://doi.org/10.1016/j.jneuroim.2017.11.008
Lisboa, S. F. S., Issy, A. C., Biojone, C., Montezuma, K., Fattori, V., Del-Bel, E. A., Guimaraes, F. S., Cunha, F. Q., Verri, W. A. & Joca, S. R. L. (2018). Mice lacking interleukin-18 gene display behavioral changes in animal models of psychiatric disorders: Possible involvement of immunological mechanisms. Journal of Neuroimmunology.
Martis, L.-S., Brision, C., Holmes, M. C. & Wiborg, O. (2018). Resilient and depressive-like rats show distinct cognitive impairments in the touchscreen paired-associates learning (PAL) task. Neurobiology of Learning and Memory, 155, 287-296. https://doi.org/10.1016/j.nlm.2018.08.014
Martis, L.-S., Tran, T. P., Bouzinova, E., Christiansen, S. L., Møller, A., Holmes, M. C. & Wiborg, O. (2018). The effect of rat strain and stress exposure on performance in touchscreen tasks. Physiology & Behavior, 184, 83-90. https://doi.org/10.1016/j.physbeh.2017.11.010
Masana, M., Westerholz, S., Kretzschmar, A., Treccani, G., Liebl, C., Santarelli, S., Dournes, C., Popoli, M., Schmidt, M. V., Rein, T. & Müller, M. B. (2018). Expression and glucocorticoid-dependent regulation of the stress-inducible protein DRR1 in the mouse adult brain. Brain Structure and Function, 223(9), 4039–4052. https://doi.org/10.1007/s00429-018-1737-7
Mortensen, J. K., Kraglund, K. L., Johnsen, S. P., Mors, O., Andersen, G. & Buttenschøn, H. N. (2018). The Serotonin Transporter Gene Polymorphisms and Risk of Ischemic Stroke. Cerebrovascular Diseases, 45(3-4), 187-192. https://doi.org/10.1159/000488364
Paternoster, V., Rajkumar, A. P., Nyengaard, J. R., Børglum, A. D., Grove, J. & Christensen, J. H. (2018). The importance of data structure in statistical analysis of dendritic spine morphology. Journal of Neuroscience Methods, 296, 93-98. https://doi.org/10.1016/j.jneumeth.2017.12.022
Pedersen, K., Bertelsen, A. & Mors, O. (Ed.) (2018). Present State Examination: Kort version til klinisk brug. (5 ed.) Munksgaard .
Pehrson, A. L., Pedersen, C. S., Tølbøl, K. S. & Sanchez, C. (2018). Vortioxetine treatment reverses subchronic PCP treatment-induced cognitive impairments: A potential role for serotonin receptor-mediated regulation of GABA neurotransmission. Frontiers in Pharmacology, 9(MAR), Article 162. https://doi.org/10.3389/fphar.2018.00162
Pereira, V. S. & Hiroaki-Sato, V. A. (2018). A brief history of antidepressant drug development: From tricyclics to beyond ketamine. Acta Neuropsychiatrica, 30(6), 307-322. https://doi.org/10.1017/neu.2017.39
